Fly stage trypanosomes recycle glucose catabolites and TCA cycle intermediates to stimulate growth in near physiological conditions
O. Villafraz, M. Biran, E. Pineda, N. Plazolles, E. Cahoreau, R. Ornitz, T. Magali, S. Allmann, E. Tetaud, L. Riviere, A. Silber, M. P. Barrett, A. Zikova, M. Boshart, J.-C. Portais, F. Bringaud
This study shows procyclic trypanosomes can use TCA cycle intermediates and glucose catabolites for growth in the fly midgut, expanding their metabolic flexibility.
bioRxiv · Dec 17, 2020Microbiology