Author

S. Anang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 6

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 6 Organism:human· 6 Assay:proteomics· 3

Frequent Co-Authors

J. G. Sodroski· 5 shared A. B. Smith· 3 shared N. Madani· 3 shared Q. Wang· 3 shared T.-J. Chiu· 3 shared A. Finzi· 2 shared C. Bourassa· 2 shared H. T. Nguyen· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersMicrobiology

J. G. Sodroski

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

V3 tip determinants of susceptibility to inhibition by CD4-mimetic compounds in natural clade A human immunodeficiency virus (HIV-1) envelope glycoproteins

S. Anang, S. Zhang, C. Fritschi, T.-J. Chiu, A. B. Smith, N. Madani, J. G. Sodroski

This study identifies residue changes in the gp120 V3 loop that influence susceptibility of HIV-1 Envs to CD4-mimetic compounds, showing how variations outside the binding site affect inhibitor sensitivity.

bioRxiv · Jul 31, 2023Microbiology

Indoline CD4-mimetic Compounds Mediate Potent and Broad HIV-1 Inhibition and Sensitization to Antibody-dependent Cellular Cytotoxicity

C. J. Fritschi, S. Anang, Z. Gong, M. Mohammadi, J. Richard, C. Bourassa, K. T. Severino, H. Richter, D. Yang, H.-C. Chen, T.-J. Chiu, M. Seaman, N. Madani, C. Abrams, A. Finzi, , A. B. Smith

This study designs and evaluates indoline-based CD4-mimetic compounds that inhibit HIV-1 more potently and broadly than existing indane-based compounds and sensitize HIV-1 to antibody-dependent cellular cytotoxicity.

bioRxiv · Jan 2, 2023 · PreprintMicrobiology

Characterization of the Human Immunodeficiency Virus (HIV-1) Envelope Glycoprotein Conformational States on Infectious Virus Particles

H. T. Nguyen, Q. Wang, S. Anang, J. G. Sodroski

This paper characterizes HIV-1 Env conformational states on virions and shows how stabilizing the pretriggered State-1 conformation enhances bNAb recognition and reduces shedding.

bioRxiv · Dec 1, 2022Microbiology

Characterization of human immunodeficiency virus (HIV-1) envelope glycoprotein variants selected for resistance to a CD4-mimetic compound

S. Anang, J. Richard, C. Bourassa, G. Goyette, T.-J. Chiu, H.-C. Chen, A. B. Smith, N. Madani, A. Finzi, J. G. Sodroski

This study identifies HIV-1 Env variants resistant to CD4-mimetic compounds and BMS-806 by analyzing mutations that confer resistance and their effects on viral fitness and inhibitor sensitivity.

bioRxiv · Apr 21, 2022Microbiology

Functional properties of the spike glycoprotein of the emerging SARS-CoV-2 variant B.1.1.529

Q. Wang, S. Anang, S. Iketani, Y. Guo, L. Liu, D. D. Ho, J. G. Sodroski

This study compares the functional properties of the B.1.1.529 SARS-CoV-2 spike glycoprotein with previous variants, finding reduced processing and lower stability but equivalent infection efficiency and increased ACE2 binding affinity.

bioRxiv · Dec 27, 2021Microbiology

Spike glycoprotein and host cell determinants of SARS-CoV-2 entry and cytopathic effects

H. T. Nguyen, S. Zhang, Q. Wang, S. Anang, J. Wang, H. Ding, J. C. Kappes, J. G. Sodroski

This study identifies key features of the SARS-CoV-2 spike glycoprotein, including the furin cleavage site and D614G mutation, that influence viral infectivity, stability, and cytopathicity.

bioRxiv · Oct 22, 2020Microbiology