Author

S. C. Lakhotia

Primary ORCID profile (0000-0003-1842-8411 · 8 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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S. C. LakhotiaiD8 papers · Banaras Hindu University

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Organism:Drosophila· 4 Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 3 Research Focus:cell signaling & trafficking· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

G. Singh· 3 shared A. Bajpai· 1 shared A. Biswas· 1 shared A. G. Goodman· 1 shared A. Goel· 1 shared B. Ateeq· 1 shared D. Sinha· 1 shared M. Ray· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersCell Biology

G. Singh

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Author profile →

4 papers

Recent·Most cited

Non-canonically regulated heterochronic expression of Hsp70 drives clonal expansion and invasion in Drosophila epithelial tumors

A. Biswas, G. Singh, V. Arya, S. C. Lakhotia, D. Sinha

This study shows that non-canonical Hsp70 regulation via ROS-JNK-FOXO pathway drives clonal expansion and invasion in Drosophila epithelial tumors.

bioRxiv · Feb 2, 2023Cell Biology

Elevation of major constitutive heat shock proteins is heat shock factor independent and essential for establishment and growth of Lgl loss and Yorkie gain mediated tumors in Drosophila

G. Singh, S. Chakraborty, S. C. Lakhotia

This study shows that constitutive heat shock proteins, not stress-inducible Hsp70, are essential for tumor growth in Drosophila, independent of HSF regulation.

Cell Stress and Chaperones · Jul 1, 2022Peer-reviewedCancer Biology

Nuclear biocondensate-forming lncRNA and cellular stress surveillance shape host cancer susceptibility

A. Bajpai, Q. T. Ahmad, S. Kundu, R. K. Pandey, A. G. Goodman, A. Goel, B. Ateeq, S. C. Lakhotia, P. Sinha

This study identifies hsr{omega} and its human homologs as key regulators of cancer susceptibility through stress response pathways in Drosophila and humans.

bioRxiv · Apr 26, 2021 · PreprintCancer Biology

Altered levels of hsromega lncRNAs further enhance Ras signaling during ectopically activated Ras induced R7 differentiation in Drosophila

M. Ray, G. Singh, S. C. Lakhotia

The paper shows that altering hsr{omega} lncRNA levels enhances Ras signaling in Drosophila eye discs, leading to increased R7 photoreceptors and pupal lethality.

bioRxiv · Apr 13, 2019Cell Biology