Author

S. D. Lehoux

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

R. D. Cummings· 5 shared A. Anzurez· 1 shared A. S. Weyrich· 1 shared B. A. Cobb· 1 shared B. J. Jenkins· 1 shared B. K. Manne· 1 shared B. X. Wang· 1 shared C. C. Yost· 1 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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5 shared papersBiochemistry

R. D. Cummings

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Author profile →

5 papers

Recent·Most cited

Plasma ST6Gal1 is Dispensable for IgG Sialylation

D. M. Oswald, S. D. Lehoux, J. Y. Zhou, L. M. Glendenning, R. D. Cummings, B. A. Cobb

The paper shows that plasma ST6Gal1 is not required for IgG 2,6-sialylation, as IgG sialylation remains normal in mice lacking ST6Gal1 in hepatocytes or B cells.

bioRxiv · Feb 1, 2022Immunology

Mucin glycans signal through the sensor kinase RetS to inhibit virulence-associated traits in Pseudomonas aeruginosa

B. X. Wang, K. M. Wheeler, K. C. Cady, S. D. Lehoux, R. D. Cummings, M. T. Laub, K. Ribbeck

This study shows that mucin glycans activate RetS in Pseudomonas aeruginosa, inhibiting virulence traits by suppressing the GacS-GacA system and type VI secretion system.

bioRxiv · Mar 31, 2020Microbiology

Differential glycosylation of alpha-1-acid glycoprotein (AGP-1) contributes to its functional diversity.

M. S. Sumanth, S. P. Jacob, K. V. Abhilasha, B. K. Manne, V. Basrur, S. D. Lehoux, R. A. Campbell, C. C. Yost, M. T. Rondina, T. M. McIntyre, R. D. Cummings, A. S. Weyrich, G. K. Marathe

This study shows that differential glycosylation of AGP-1 leads to distinct functional effects on neutrophils and platelets during inflammation.

bioRxiv · Feb 27, 2020Biochemistry

The schizophrenia risk locus in SLC39A8 alters brain metal transport and plasma glycosylation

R. G. Mealer, B. J. Jenkins, C.-Y. Chen, M. J. Daly, T. Ge, S. D. Lehoux, T. Marquardt, C. D. Palmer, J. H. Park, P. J. Parsons, R. Sackstein, S. E. Williams, R. D. Cummings, E. M. Scolnick, J. W. Smoller

The paper investigates how a common SLC39A8 variant affects brain metal transport and plasma glycosylation in schizophrenia, identifying manganese-related changes and potential biomarkers.

bioRxiv · Jan 14, 2020Biochemistry

Glycosylation of Zika Virus Is Important in Host-Virus Interaction and Pathogenesis

N. K. Routhu, S. D. Lehoux, E. A. Rouse, M. R. M. Bidokhti, L. B. Giron, A. Anzurez, S. P. Reid, M. Abdel-Mohsen, R. D. Cummings, S. N. Byrareddy

This study maps N-glycans on ZIKV E proteins and shows their role in viral entry via host lectins, highlighting their importance in pathogenesis.

bioRxiv · Mar 1, 2019 · PreprintBiochemistry