M. Abdel-Mohsen

Immune Correlates of Hyperglycemia and Vaccination in a Non-human Primate Model of Long-COVID

This study establishes a non-human primate model of metabolic PASC, identifies immune correlates of hyperglycemia, and shows vaccine-induced glycemic improvement.

Human Galectin-9 Promotes the Expansion of HIV Reservoirs in vivo in Humanized Mice

This study shows that Gal-9 treatment during ART increases HIV DNA and RNA in tissues of humanized mice, suggesting it promotes HIV persistence.

Markers of Fungal Translocation Are Elevated During Post-Acute Sequelae of SARS-CoV-2 Infection and Induce NF-κB Triggered Inflammation.

This study identifies elevated fungal translocation markers in PASC patients, which induce NF-κB inflammation through Dectin-1 signaling.

CyTOF-Lec: Single-cell glycomics analysis reveals glycan features defining cells differentially susceptible to HIV

This study develops CyTOF-Lec to analyze glycan features in human immune cells, revealing that sialic acid levels distinguish HIV-susceptible memory CD4+ T cells.

COVID-19 Severity Is Associated with Differential Antibody Fc-mediated Innate Immune Functions

The paper examines how differences in antibody-mediated innate immune functions correlate with COVID-19 severity.

Phospholipid Metabolism Is Associated with HIV Rebound Upon Treatment Interruption

This study links phospholipid and lysophospholipid levels to faster HIV rebound after treatment interruption, suggesting their role in viral persistence and inflammation.

Non-Invasive Plasma Glycomic and Metabolic Biomarkers of Post-treatment Control of HIV

This study identifies non-invasive plasma glycomic and metabolic biomarkers that predict viral rebound after HIV treatment interruption with high accuracy.

The genetic interaction between HIV and the antibody repertoire

The paper analyzes HIV and antibody repertoire interactions in longitudinal samples, finding enriched V gene segments in HIV-associated AbR partitions but little evidence of antagonistic coevolution.

Glycosylation of Zika Virus Is Important in Host-Virus Interaction and Pathogenesis

This study maps N-glycans on ZIKV E proteins and shows their role in viral entry via host lectins, highlighting their importance in pathogenesis.

Chromatin Functional States Correlate with HIV Latency Reversal in Infected Primary CD4+ T Cells

The paper identifies that latency reversing agents reactivate less than 5% of latent HIV proviruses and shows distinct chromatin functional states between reactivated and non-reactivated cells.