Author

S. Ekström

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:proteomics· 3 Organism:bacteria (other)· 2 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1

Frequent Co-Authors

E. Hjortswang· 2 shared J. Malmström· 2 shared L. Malmström· 2 shared A. Bläckberg· 1 shared A. Gomez Toledo· 1 shared A. Izadi· 1 shared A. Pankow· 1 shared B. Murrell· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBiochemistry

E. Hjortswang

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Multi-Modal Mass Spectrometry Identifies a Conserved Protective Epitope in S. pyogenes Streptolysin O

D. Tang, C. A. Gueto-Tettay, E. Hjortswang, J. Ströbaek, S. Ekström, L. Happonen, L. Malmström, J. Malmström

This study uses multi-modal mass spectrometry to identify a conserved protective epitope in Streptolysin O from S. pyogenes, which could inform vaccine and therapeutic development.

bioRxiv · Dec 2, 2023 · PreprintBiochemistry

Dissecting the properties of circulating IgG against Group A Streptococcus through a combined systems antigenomics-serology workflow

S. Chowdhury, A. Gomez Toledo, E. Hjortswang, J. T. Sorrentino, N. E. Lewis, A. Bläckberg, S. Ekström, A. Izadi, P. Nordenfelt, L. Malmström, M. Rasmussen, J. Malmström

This paper develops a combined systems antigenomics-serology workflow to characterize circulating IgG against Group A Streptococcus, revealing antigen repertoire and functional properties of antibodies in healthy and infected individuals.

bioRxiv · Nov 7, 2023 · PreprintImmunology

Activity modulation in anaerobic ribonucleotide reductases: nucleotide binding to the ATP-cone allosterically mediates substrate binding to the active site

O. Bimai, I. Banerjee, I. R. Grinberg, P. Huang, L. Hultgren, S. Ekström, D. Lundin, B.-M. Sjöberg, D. T. Logan

This study investigates how ATP and dATP binding to the ATP-cone of anaerobic RNR from Prevotella copri modulates enzyme activity through structural and biochemical changes.

bioRxiv · Jun 20, 2023Biochemistry

Multivariate mining of an alpaca immune repertoire identifies potent cross-neutralising SARS-CoV-2 nanobodies

L. Hanke, D. J. Sheward, A. Pankow, L. Perez Vidakovics, V. Karl, C. Kim, E. Urgard, N. L. Smith, J. Astorga-Wells, S. Ekström, J. M. Coquet, G. M. McInerney, B. Murrell

This study identifies potent cross-neutralizing SARS-CoV-2 nanobodies from an alpaca immune repertoire using phage display and epitope mapping.

bioRxiv · Jul 25, 2021Immunology

Structure dynamics of ApoA-I amyloidogenic variants in small HDL increase their ability to mediate cholesterol efflux

J. O. Lagerstedt, O. Nilsson, M. Lindvall, L. Obici, S. Ekström, R. Del Giudice

The paper shows that ApoA-I amyloidogenic variants form smaller HDL particles with enhanced cholesterol efflux capacity, explaining reduced cardiovascular risk despite lower HDL-cholesterol levels.

bioRxiv · Apr 8, 2020Biochemistry