The human nose organoid respiratory virus model: an ex-vivo human challenge model to study RSV and SARS-CoV-2 pathogenesis and evaluate therapeutics
A. Rajan, A. M. Weaver, G. M. Alosio, J. Jelinski, H. L. Johnson, S. F. Venable, T. McBride, L. Aideyan, F.-A. Piedra, X. Ye, E. Melicoff-Portillo, M. R. K. Yerramilli, X.-L. Zeng, M. A. Mancini, F. Stossi, , P. A. Piedra
This paper develops a non-invasive human nose organoid model to study RSV and SARS-CoV-2 infection and test therapeutics like palivizumab.
bioRxiv · Jul 28, 2021Microbiology