Author

X.-L. Zeng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Organism:human· 4 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

M. K. Estes· 5 shared A. Kambal· 2 shared A. Rajan· 2 shared A. W. Maresso· 2 shared F. Stossi· 2 shared S. Blutt· 2 shared S. E. Crawford· 2 shared S. Ramani· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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5 shared papersMicrobiology

M. K. Estes

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Functional Genomics of Gastrointestinal Escherichia coli Isolated from Patients with Cancer and Diarrhea

H. Carter, J. Clark, L. G. Carlin, E. Vaughan, A. Rajan, A. Olvera, X. Yu, X.-L. Zeng, A. Kambal, M. Holder, X. Qin, R. A. Gibbs, J. F. Petrosino, D. M. Muzny, H. Doddapaneni, , P. C. Okhuysen

The paper investigates E. coli strains from cancer patients with diarrhea, finding novel adherence patterns and high antibiotic resistance gene carriage.

bioRxiv · May 31, 2023 · PreprintMicrobiology

Infant and Adult Human Intestinal Enteroids are Morphologically and Functionally Distinct

G. O. Adeniyi-Ipadeola, J. D. Hankins, A. Kambal, X.-L. Zeng, K. Patil, V. Poplaski, C. Bomidi, H. Nguyen-Phuc, S. L. Grimm, C. Coarfa, F. Stossi, S. E. Crawford, S. E. Blutt, A. L. Speer, M. K. Estes, S. Ramani

This study compares infant and adult human intestinal enteroids, finding significant transcriptomic, morphological, and functional differences that highlight their distinct characteristics.

bioRxiv · May 19, 2023Microbiology

The human nose organoid respiratory virus model: an ex-vivo human challenge model to study RSV and SARS-CoV-2 pathogenesis and evaluate therapeutics

A. Rajan, A. M. Weaver, G. M. Alosio, J. Jelinski, H. L. Johnson, S. F. Venable, T. McBride, L. Aideyan, F.-A. Piedra, X. Ye, E. Melicoff-Portillo, M. R. K. Yerramilli, X.-L. Zeng, M. A. Mancini, F. Stossi, , P. A. Piedra

This paper develops a non-invasive human nose organoid model to study RSV and SARS-CoV-2 infection and test therapeutics like palivizumab.

bioRxiv · Jul 28, 2021Microbiology

New Insights and Enhanced Human Norovirus Cultivation in Human Intestinal Enteroids

K. Ettayebi, V. R. Tenge, N. W. Cortes-Penfield, S. E. Crawford, F. H. Neill, X.-L. Zeng, X. Yu, V. B. Ayyar, D. Burrin, S. Ramani, R. L. Atmar, M. K. Estes

This paper optimizes human intestinal enteroid culture conditions to enhance cultivation of diverse human norovirus strains and improves replication consistency over time.

bioRxiv · Nov 12, 2020Microbiology

Isolation, culture and maintenance of rabbit intestinal organoids, and organoid-derived cell monolayers

E. Kardia, M. Frese, T. Strive, X.-L. Zeng, M. K. Estes, R. N. Hall

This paper establishes a protocol for isolating and maintaining rabbit intestinal organoids and monolayers, demonstrating their ability to mimic intestinal epithelium and support pathogen research.

bioRxiv · Jul 15, 2020 · PreprintCell Biology