Author

S. Hamperl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:chromatin & epigenetic regulation· 3 Organism:human· 3 Assay:DNA methylation· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Chanou· 2 shared C. S. K. Lee· 2 shared E. Kruse· 2 shared H. Ummethum· 2 shared M. Lalonde· 2 shared M. Trauner· 2 shared M. Weiss· 2 shared M. Werner· 2 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBiochemistry

A. Chanou

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Single molecule MATAC-seq reveals key determinants of DNA replication origin efficiency

A. Chanou, M. Weiss, K. Holler, T. Straub, J. Krietsch, A. Sanchi, H. Ummethum, C. S. K. Lee, E. Kruse, M. Trauner, M. Werner, M. Lalonde, M. Lopes, A. Scialdone, S. Hamperl

The paper develops MATAC-Seq to analyze single-molecule chromatin accessibility at replication origins, identifying chromatin features that predict origin efficiency in yeast.

bioRxiv · Mar 14, 2023Biochemistry

The CGG triplet repeat binding protein 1 counteracts DNA secondary structure-induced transcription-replication conflicts

H. Ummethum, M. Lalonde, M. Werner, M. Trauner, A. Chanou, M. Weiss, C. S. K. Lee, E. Kruse, A. Ettinger, S. Hamperl

This study shows CGGBP1 binds to short trinucleotide repeats to prevent transcription-replication conflicts caused by secondary DNA structures.

bioRxiv · Mar 9, 2023 · PreprintCell Biology

The first days in the life of naïve human B-lymphocytes infected with Epstein-Barr virus

D. Pich, P. Mrozek-Gorska, M. Bouvet, A. Sugimoto, E. Akidil, A. Grundhoff, S. Hamperl, P. Ling, W. Hammerschmidt

This study identifies EBNA2 as essential for early EBV infection of naive B-cells, showing it drives activation, proliferation, and prevents cell death, while other latent genes have minimal or no effect during the pre-latent phase.

bioRxiv · Jun 11, 2019Microbiology

DNA Replication Modulates R-loop Levels to Maintain Genome Stability

S. Hamperl, J. C. Saldivar, M. J. Bocek, K. A. Cimprich

This study shows that DNA replication orientation affects R-loop formation, with the replisome reducing R-loops in co-directional conflicts but promoting them in head-on conflicts, leading to genome instability.

bioRxiv · Jun 26, 2017Cell Biology