S. Hewitt

SARS-CoV-2 Infection of Salivary Glands Compromises Oral Antifungal InnateImmunity and Predisposes to Oral Candidiasis

This study shows SARS-CoV-2 infection reduces histatin-5 in salivary glands, impairing antifungal immunity and increasing Candida albicans prevalence in COVID-19 patients.

HIV viral protein R induces loss of DCT1-type renal tubules

This study shows HIV Vpr reduces DCT1-type renal tubules in mice, leading to salt wasting via apoptosis dysregulation of Slc12a3+ Pvalb+ cells.

Evidence for pre-climacteric activation of AOX transcription during cold-induced conditioning to ripen in European pear (Pyrus communis L.)

The paper investigates cold-induced ripening in European pears, finding that AOX transcript abundance increases pre-climacterically, suggesting a novel role in ripening competency.

Concomitant phytonutrient and transcriptome analysis of mature fruit and leaf tissues of tomato (Solanum lycopersicum L. cv. Oregon Spring) grown using organic and conventional fertilizer

The paper compares phytonutrient and transcriptome profiles of tomato tissues under organic and conventional fertilizers, finding differential gene expression and metabolic shifts in organic conditions.

Integrated proteogenomic analysis of metastatic thoracic tumors identifies APOBEC mutagenesis and copy number alterations as drivers of proteogenomic tumor evolution and heterogeneity