S. Imamura

Non-cell-adhesive hydrogel promotes formation of human blastoid from primed human pluripotent stem cells.

A non-cell-adhesive hydrogel enables blastoid formation from primed hPSC, mimicking blastocyst structure and differentiation.

Gut-liver-axis microphysiological system for studying cellular fluidic shear stress and inter-tissue interaction

This paper introduces a gut-liver-axis microphysiological system that applies physiologically relevant fluid shear stress to gut and liver cells, enhancing their survival and functional protein expression.

Cyclo olefin polymer-based solvent-free mass-productive microphysiological systems

The paper develops a cyclo olefin polymer-based microphysiological system to improve drug screening and toxicological testing by avoiding material-related issues.

Recapitulation of human embryonic heart beating to promote differentiation of hepatic endoderm to hepatoblasts

The paper uses a microfluidic platform to simulate human heart beats, enhancing the functional properties of hepatoblasts derived from hepatic endoderm.

Heat treatment functionalizes hepatocyte-like cells derived from human embryonic stem cells.

This study shows that culturing hepatocyte-like cells from human embryonic stem cells at 39°C improves hepatic functions like albumin secretion and CYP3A4 activity without significant cell death.

Evaluation of host effects on ectomycorrhizal fungal community compositions in a forest landscape in northern Japan

The paper evaluates how host species influence ectomycorrhizal fungal community compositions in a forest landscape, finding host preference is a primary determinant.