Author

S. Jazani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 8

Signature Assays, Organisms & Methods

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Assay:fluorescence / live-cell microscopy· 7 Approach:Bayesian inference· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

S. Presse· 6 shared I. Sgouralis· 4 shared M. Levitus· 2 shared M. Tavakoli· 2 shared O. M. Shafraz· 2 shared S. Sivasankar· 2 shared T. Ha· 2 shared A. Vallmitjana· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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6 shared papersBiophysics

S. Presse

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Author profile →

8 papers

Recent·Most cited

Single-Molecule Reaction-Diffusion

L. W. Q. Xu, S. Jazani, Z. Kilic, S. Presse

This paper introduces Bayes-smRD, a method to analyze single-molecule reaction-diffusion using photon arrival data, revealing molecule-specific properties with reduced data and photodamage.

bioRxiv · Sep 5, 2023Biophysics

Dynamic 1D Search and Processive Nucleosome Translocations by RSC and ISW2 Chromatin Remodelers

J. M. Kim, C. C. Carcamo, S. Jazani, Z. Xie, X. A. Feng, M. Yamadi, M. F. Poyton, K. L. Holland, J. B. Grimm, L. D. Lavis, T. Ha, C. Wu

This study investigates the dynamic search and processive nucleosome translocation mechanisms of RSC and ISW2 chromatin remodelers using optical tweezers and single-particle imaging.

bioRxiv · Jun 13, 2023Biophysics

Fluorescence lifetime analysis of smFRET with contribution of PIFE on donor and acceptor

S. Jazani, T. Ha

This paper develops a Bayesian framework to analyze smFRET data and separate PIFE effects from FRET efficiency changes using fluorescence lifetime signals.

bioRxiv · Apr 3, 2023 · PreprintBiophysics

Building Fluorescence Lifetime Maps Photon-by-photon by Leveraging Spatial Correlations

M. Fazel, S. Jazani, L. Scipioni, A. Vallmitjana, S. Zhu, E. Gratton, M. Digman, S. Presse

This paper introduces a doubly nonparametric framework for FLIM that learns fluorescent species and absolute lifetime maps while addressing spatial correlations and low photon counts.

bioRxiv · Nov 29, 2022Biophysics

A computational proposal for tracking multiple molecules in a multi-focus confocal setup

S. Jazani, L. Xu, I. Sgouralis, D. P. Shepherd, S. Presse

This paper proposes a computational method to track multiple fluorescent molecules in a multi-focus confocal setup, enabling 3D high-speed tracking below the diffraction limit.

bioRxiv · May 17, 2022 · PreprintBiophysics

Direct Photon-by-photon Analysis of Time-Resolved Pulsed Excitation Data using Bayesian Nonparametrics

M. Tavakoli, S. Jazani, I. Sgouralis, W. Heo, K. Ishii, T. Tahara, S. Presse

This paper introduces a Bayesian nonparametric method to directly infer the number of chemical species and their lifetimes from photon arrival data without pre-specifying the number of species.

Cell Reports Physical Science · Nov 1, 2020Peer-reviewedBiophysics

Pitching single focus confocal data analysis one photon at a time with Bayesian nonparametrics

M. Tavakoli, S. Jazani, I. Sgouralis, O. M. Shafraz, B. Donaphon, S. Sivasankar, M. Levitus, S. Presse

This paper introduces a Bayesian nonparametric method to analyze single-focus confocal data by directly processing photon arrival times, enabling faster and more efficient molecular dynamics analysis than traditional methods.

bioRxiv · Apr 16, 2020Biophysics

An Alternative Framework for Fluorescence Correlation Spectroscopy

S. Jazani, I. Sgouralis, O. M. Shafraz, M. Levitus, S. Sivasankar, S. Presse

This paper introduces a new analysis method for fluorescence correlation spectroscopy that enables faster and less phototoxic analysis of single molecule fluorescence confocal microscopy data.

bioRxiv · Apr 16, 2019Biophysics