Author

K. L. Holland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Approach:microscopy & imaging analysis· 2 Research Focus:cell signaling & trafficking· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Assay:imaging· 1 Research Focus:imputation· 1

Frequent Co-Authors

L. D. Lavis· 3 shared J. B. Grimm· 2 shared T. A. Daugird· 2 shared W. R. Legant· 2 shared A. N. Tkachuk· 1 shared A. Sau· 1 shared B. D. Strahl· 1 shared B. P. English· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersBiophysics

L. D. Lavis

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Author profile →

3 papers

Recent·Most cited

A series of spontaneously blinking dyes for super-resolution microscopy

K. L. Holland, S. E. Plutkis, T. A. Daugird, A. Sau, J. B. Grimm, B. P. English, Q. Zheng, S. Dave, F. Rahman, L. Xie, P. Dong, A. N. Tkachuk, T. A. Brown, R. H. Singer, Z. J. Liu, , L. D. Lavis

This paper introduces a series of spontaneously blinking dyes with adjustable duty cycles for improved single-molecule localization microscopy in cells and dense structures.

bioRxiv · Feb 23, 2024Cell Biology

Correlative single molecule lattice light sheet imaging reveals the dynamic relationship between nucleosomes and the local chromatin environment

T. A. Daugird, Y. Shi, K. L. Holland, H. Rostamian, Z. Liu, L. D. Lavis, J. Rodriguez, B. D. Strahl, W. R. Legant

The paper uses correlative single molecule lattice light sheet imaging to study nucleosome dynamics and chromatin environment interactions in live cells, revealing differential diffusion and packing with increasing chromatin density.

bioRxiv · Nov 9, 2023Biophysics

Dynamic 1D Search and Processive Nucleosome Translocations by RSC and ISW2 Chromatin Remodelers

J. M. Kim, C. C. Carcamo, S. Jazani, Z. Xie, X. A. Feng, M. Yamadi, M. F. Poyton, K. L. Holland, J. B. Grimm, L. D. Lavis, T. Ha, C. Wu

This study investigates the dynamic search and processive nucleosome translocation mechanisms of RSC and ISW2 chromatin remodelers using optical tweezers and single-particle imaging.

bioRxiv · Jun 13, 2023Biophysics