Author

S. K. Bhattarai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

B. M. Mortzfeld· 4 shared V. Bucci· 4 shared B. A. McCormick· 2 shared A. L. Zeamer· 1 shared A. Reboldi· 1 shared C. Bang· 1 shared C. C. Neto· 1 shared D. Ward· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersMicrobiology

B. M. Mortzfeld

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Microbiota encoded fatty-acid metabolism expands tuft cells to protect tissues homeostasis during Clostridioides difficile infection in the large intestine

T. D. Kellogg, S. Ceglia, B. M. Mortzfeld, A. L. Zeamer, S. E. Foley, D. Ward, S. K. Bhattarai, B. A. McCormick, A. Reboldi, V. Bucci

This study shows that succinate from the microbiota expands tuft cells in the colon, enhancing type 2 immunity and reducing C. difficile-induced disease.

bioRxiv · Jan 29, 2024 · PreprintImmunology

Expanding the toolbox: Novel class IIb microcins show activity against gram-negative ESKAPE and plant pathogens

B. M. Mortzfeld, S. K. Bhattarai, V. Bucci

The paper identifies twelve new class IIb microcins from seven Enterobacteriaceae species and validates their activity against Gram-negative pathogens and plant pathogens.

bioRxiv · Dec 5, 2023Microbiology

Microcin MccI47 selectively inhibits enteric bacteria and reduces carbapenem-resistant Klebsiella pneumoniae colonization in vivo when administered via an engineered live biotherapeutic

B. M. Mortzfeld, J. D. Palmer, S. K. Bhattarai, H. L. Dupre, R. Mercado-Lubo, M. W. Silby, C. Bang, B. A. McCormick, V. Bucci

This paper demonstrates that engineered live biotherapeutic Escherichia coli producing microcin MccI47 reduces carbapenem-resistant Klebsiella pneumoniae colonization in mice without disrupting the microbiota.

Gut Microbes · Sep 29, 2022Peer-reviewedBioengineering

Proanthocyanidin-enriched cranberry extract induces resilient bacterial community dynamics in a gnotobiotic mouse model

C. C. Neto, B. M. Mortzfeld, J. R. Turbitt, S. K. Bhattarai, V. Yeliseyev, N. DiBenedetto, L. M. Bry, V. Bucci

This study shows that a proanthocyanidin-enriched cranberry extract alters bacterial community dynamics in a gnotobiotic mouse model, with transient increases in mucin-degrading and anti-inflammatory bacteria.

bioRxiv · Feb 25, 2021Microbiology