Author

S. K. Sivasankaran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 3 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 5 Assay:bulk RNA-seq· 4 Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Assay:scRNA-seq· 4 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Research Focus:cell-cell communication· 2

Frequent Co-Authors

C. L. Loving· 3 shared J. E. Wiarda· 3 shared C. K. Tuggle· 2 shared S. Devineau· 2 shared S. Fanning· 2 shared S. Srikumar· 2 shared A. A. Miranda-CasoLuengo· 1 shared A. Bhargava· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersImmunology

C. L. Loving

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Author profile →

7 papers

Recent·Most cited

Conserved B cell signaling, activation, and differentiation in porcine jejunal and ileal Peyer's patches despite distinct immune landscapes

J. E. Wiarda, A. L. Shircliff, J. B. Stasko, S. K. Sivasankaran, M. R. Ackermann, C. L. Loving

The paper uses single-cell and spatial transcriptomics to study B cell dynamics in porcine Peyer's patches, finding conserved signaling and differentiation despite location-specific immune landscapes.

bioRxiv · Sep 12, 2023Immunology

Cellular characterization of the mouse collecting lymphatic vessels reveals that lymphatic muscle cells are the innate pacemaker cells

S. D. Zawieja, G. A. Pea, S. E. Broyhill, A. Patro, K. H. Bromert, C. E. Norton, H. J. Kim, S. K. Sivasankaran, M. Li, J. A. Castorena-Gonzalez, B. T. Drumm, M. J. Davis

This study identifies lymphatic muscle cells as the pacemaker cells in mouse collecting lymphatic vessels through combined immunofluorescence, scRNA-seq, and electrophysiological analyses.

bioRxiv · Aug 24, 2023Physiology

Porcine intestinal innate lymphoid cells and lymphocyte spatial context revealed through single-cell RNA sequencing

J. E. Wiarda, J. M. Trachsel, S. K. Sivasankaran, C. K. Tuggle, C. L. Loving

This study uses scRNA-seq to characterize porcine ileal lymphocytes, identifying novel cell types and spatial patterns, and develops tools for their further analysis.

bioRxiv · Jan 9, 2022Immunology

Reference transcriptomes of porcine peripheral immune cells created through bulk and single-cell RNA sequencing

J. Herrera-Uribe, J. E. Wiarda, S. K. Sivasankaran, L. Daharsh, H. Liu, K. A. Byrne, T. Smith, J. K. Lunney, C. L. Loving, C. K. Tuggle

The paper defines porcine peripheral blood immune cell transcriptomes using bulk and single-cell RNA sequencing, revealing similarities to human data and providing resources for immunogenetic studies.

bioRxiv · Apr 2, 2021Immunology

Silver nanoparticles induce a triclosan-like antibacterial action mechanism in multi-drug resistant Klebsiella pneumoniae

V. Pareek, S. Devineau, S. K. Sivasankaran, A. Bhargava, J. Panwar, S. Srikumar, S. Fanning

This study shows silver nanoparticles induce a triclosan-like antibacterial mechanism in multi-drug resistant Klebsiella pneumoniae by inhibiting fatty acid biosynthesis and causing oxidative stress.

bioRxiv · Oct 24, 2020Microbiology

Analysis of the oxidative stress regulon identifies soxS as a genetic target for resistance reversal in multi-drug resistant Klebsiella pneumoniae

J. Anes, K. Dever, A. Eshwar, S. Nguyen, Y. Cao, S. K. Sivasankaran, S. Sakalauskaite, A. Lehner, S. Devineau, R. Daugelavicius, S. Fanning, S. Srikumar

This study identifies soxS as a genetic target for reversing multi-drug resistance in K. pneumoniae by analyzing its oxidative stress regulon and demonstrating its role in efflux pump regulation and tetracycline susceptibility.

bioRxiv · Aug 21, 2020Microbiology

The primary transcriptome, small RNAs, and regulation of antimicrobial resistance in Acinetobacter baumannii

C. Kröger, K. D. MacKenzie, E. Y. Al-Shabib, M. W. B. Kirzinger, D. M. Suchan, T.-C. Chao, V. Akulova, A. A. Miranda-CasoLuengo, V. A. Monzon, T. Conway, S. K. Sivasankaran, J. C. D. Hinton, K. Hokamp, A. D. S. Cameron

This study identifies transcriptome architecture and small RNAs in Acinetobacter baumannii, revealing regulatory mechanisms and antimicrobial resistance traits.

bioRxiv · Dec 19, 2017Microbiology