Author

S. Kaptan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

I. Vattulainen· 2 shared A. Brech· 1 shared B. M. H. Bruininks· 1 shared C. Freund· 1 shared D. Beyer· 1 shared F. Lolicato· 1 shared F. Perez· 1 shared G. Boncompain· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

I. Vattulainen

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Disulfide bridge-dependent dimerization triggers FGF2 membrane translocation into the extracellular space

F. Lolicato, J. Steringer, R. Saleppico, D. Beyer, J. Fernandez-Sobaberas, S. Unger, S. Klein, P. Riegerova, X. J. Schmitt, S. Kaptan, S. Wegehingel, H.-M. Mueller, C. Freund, M. Hof, R. Sachl, , W. Nickel

This paper identifies C95-C95 disulfide-bridge-mediated FGF2 dimerization as essential for membrane translocation and oligomer formation, while C77 is involved in Na,K-ATPase binding.

bioRxiv · Apr 12, 2023Biochemistry

Regulation of cell dynamics by rapid transport of integrins through the biosynthetic pathway

M. Lerche, M. Mathieu, L. Malerod, N. M. Pedersen, H. Hamidi, M. Chastney, B. M. H. Bruininks, S. Kaptan, G. Jacquemet, I. Vattulainen, P. Roca-Cusachs, A. Brech, F. Perez, G. Boncompain, S. Miserey, J. Ivaska

This study shows that integrin transport through the biosynthetic pathway rapidly alters adhesion receptor availability, enabling localized cell spreading and focal adhesion growth.

bioRxiv · Jul 12, 2022Cell Biology