Author

S. Kaushal

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1 Approach:statistical model· 1 Organism:zebrafish· 1

Frequent Co-Authors

A. Dinis· 1 shared A. K. S. Camara· 1 shared Anish VasaniD· 1 shared Donald E. IngberiD· 1 shared E. B. Thorp· 1 shared E. Gardner· 1 shared Frédéric VigneaultiD· 1 shared J. Fang· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

A. Dinis

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Augmentation of Histone Deacetylase 6 Activity Impairs Mitochondrial Respiratory Complex I in Ischemic/Reperfused Diabetic Hearts

Z.-D. Ge, S. L. Baumgardt, J. Fang, X. Fu, Y. Liu, Z. Xia, M. Zhao, L. Chen, R. Mishra, M. Gunasekaran, P. Saha, J. M. Forbess, Z. J. Bosnjak, A. K. S. Camara, J. Kersten, , S. Kaushal

This study shows that increasing HDAC6 activity impairs mitochondrial complex I in diabetic hearts subjected to ischemia/reperfusion, and that inhibiting HDAC6 improves cardiac function.

bioRxiv · Feb 21, 2023 · PreprintPharmacology & Toxicology

Target-agnostic discovery of Rett Syndrome therapeutics by coupling computational network analysis and CRISPR-enabled in vivo disease modeling

R. Novak, Tiffany Lin, S. Kaushal, Megan M. Sperry, Frédéric Vigneault, E. Gardner, Sahil Loomba, K. Shcherbina, Vishal Keshari, A. Dinis, Anish Vasan, V. Chandrasekhar, Takako Takeda, Jerrold R. Turner, Michael G. Levin, Donald E. Ingber

This paper identifies vorinostat as a potential repurposed therapy for Rett syndrome by combining computational network analysis with CRISPR-edited Xenopus models, showing efficacy across multiple organ systems.

bioRxiv · Mar 20, 2022 · PreprintNeuroscience