Author

M. Gunasekaran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Assay:proteomics· 1

Frequent Co-Authors

K. J. Tracey· 2 shared S. S. Chavan· 2 shared T. Tsaava· 2 shared U. Andersson· 2 shared A. K. S. Camara· 1 shared A. M. Kressel· 1 shared A. Stiegler· 1 shared A. Tynan· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersImmunology

K. J. Tracey

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Author profile →

3 papers

Recent·Most cited

Augmentation of Histone Deacetylase 6 Activity Impairs Mitochondrial Respiratory Complex I in Ischemic/Reperfused Diabetic Hearts

Z.-D. Ge, S. L. Baumgardt, J. Fang, X. Fu, Y. Liu, Z. Xia, M. Zhao, L. Chen, R. Mishra, M. Gunasekaran, P. Saha, J. M. Forbess, Z. J. Bosnjak, A. K. S. Camara, J. Kersten, , S. Kaushal

This study shows that increasing HDAC6 activity impairs mitochondrial complex I in diabetic hearts subjected to ischemia/reperfusion, and that inhibiting HDAC6 improves cardiac function.

bioRxiv · Feb 21, 2023 · PreprintPharmacology & Toxicology

Antibody responses to immunization require sensory neurons

A. Tynan, T. Tsaava, M. Gunasekaran, I. Snee, T. Mak, P. Olofsson, U. Andersson, S. S. Chavan, K. J. Tracey

This study shows that TRPV1-expressing sensory neurons are required for antibody responses to novel antigens and that stimulating these neurons enhances antibody production.

bioRxiv · Nov 30, 2019 · PreprintImmunology

Transient Receptor Potential Ankyrin 1 Mediates Afferent Signals in the Inflammatory Reflex

H. A. Silverman, M. Gunasekaran, E. H. Chang, Q. Chang, M. E. Addorisio, A. Stiegler, A. M. Kressel, J. H. Li, T. Tsaava, T. S. Huerta, V. A. Pavlov, U. Andersson, S. S. Chavan, K. J. Tracey

This study identifies TRPA1 in vagus neurons as essential for detecting IL-1β to initiate the inflammatory reflex, reducing inflammation and improving survival in sepsis.

bioRxiv · Nov 4, 2019 · PreprintPhysiology