Author

S. Kellokumpu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Hassinen· 1 shared A. Manninen· 1 shared A. Rivinoja· 1 shared A. Samoylenko· 1 shared A. Tuomisto· 1 shared D. Mennerich· 1 shared E. Biterova· 1 shared E. Khosrowabadi· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

A. Hassinen

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

SLC4A2 Anion Exchanger Promotes Tumor Cell Malignancy via Enhancing H+ Leak across Golgi Membranes

E. Khosrowabadi, A. Rivinoja, M. Risteli, A. Tuomisto, T. Salo, M. Makinen, S. Kellokumpu

This study identifies SLC4A2 as a driver of tumor malignancy by enhancing H+ leak across Golgi membranes, leading to elevated Golgi pH and reduced glycosylation, which can be reversed by AE2 knockdown.

bioRxiv · Feb 9, 2021Cancer Biology

The pro-oncogenic adaptor CIN85 inhibits hypoxia-inducible factor prolyl hydroxylase-2

N. Kozlova, D. Mennerich, A. Samoylenko, E. Y. Dimova, P. Koivunen, E. Biterova, K. Richter, A. Hassinen, S. Kellokumpu, A. Manninen, I. Miinalainen, V. Glumoff, L. Ruddock, L. Drobot, T. Kietzmann

This study identifies CIN85 as a novel binding partner of PHD2, showing it inhibits PHD2 activity and HIF degradation, promoting tumor growth in mice.

bioRxiv · Nov 20, 2018Biochemistry