Author

N. Kozlova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

T. Muranen· 2 shared A. Hassinen· 1 shared A. L. Hillis· 1 shared A. Manninen· 1 shared A. Muller· 1 shared A. Samoylenko· 1 shared A. Toker· 1 shared B. L. Menasche· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCancer Biology

T. Muranen

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cholesterol biosynthesis inhibition synergizes with AKT inhibitors in triple-negative breast cancer

A. Toker, A. L. Hillis, T. D. Martin, H. E. Manchester, J. M. Hogstrom, N. Zhang, E. Lecky, N. Kozlova, N. S. Persky, D. E. Root, M. Brown, K. Cichowski, S. J. Elledge, T. Muranen, D. A. Fruman, , R. R. Madsen

This study identifies a synergistic effect between AKT inhibitors and pitavastatin in killing triple-negative breast cancer cells by targeting cholesterol trafficking.

bioRxiv · Jan 16, 2024 · PreprintCancer Biology

Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53

J. D. Lee, B. L. Menasche, M. Mavrikaki, M. M. Uyemura, S. M. Hong, N. Kozlova, J. Wei, M. M. Alfajaro, R. Filler, A. Muller, T. Saxena, R. R. Posey, P. Cheung, T. Muranen, J. Heng, , F. J. Slack

This study shows that SARS-CoV-2 variants differ in syncytia formation, which affects host chromatin accessibility, cellular senescence, and inflammation via TP53.

bioRxiv · Aug 31, 2023Microbiology

The pro-oncogenic adaptor CIN85 inhibits hypoxia-inducible factor prolyl hydroxylase-2

N. Kozlova, D. Mennerich, A. Samoylenko, E. Y. Dimova, P. Koivunen, E. Biterova, K. Richter, A. Hassinen, S. Kellokumpu, A. Manninen, I. Miinalainen, V. Glumoff, L. Ruddock, L. Drobot, T. Kietzmann

This study identifies CIN85 as a novel binding partner of PHD2, showing it inhibits PHD2 activity and HIF degradation, promoting tumor growth in mice.

bioRxiv · Nov 20, 2018Biochemistry