Comparative immunogenicity of bacterially expressed soluble trimers and nanoparticle displayed influenza hemagglutinin stem immunogens
U. Kar, S. Khaleeq, P. Garg, M. Bhat, P. Reddy, V. S. Vignesh, A. Upadhyaya, M. Das, C. Ghadiyaram, S. Pandey, S. Dutta, R. Varadarajan
This study compares the immunogenicity of soluble trimeric influenza stem domain immunogens and nanoparticle-displayed versions, showing similar protection against homologous and heterologous viral challenges.
bioRxiv · Mar 14, 2021Immunology