Author

S. K. Malladi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:protein sequence· 1 Organism:rat· 1

Frequent Co-Authors

M. S. Khan· 3 shared R. Singh· 3 shared R. Varadarajan· 3 shared S. Pandey· 3 shared A. J. McAuley· 2 shared A. Upadhyaya· 2 shared I. Pramanick· 2 shared K. Kanjo· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

M. S. Khan

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

SARS-CoV-2 Omicron boosting induces de novo B cell response in humans

W. B. Alsoussi, S. K. Malladi, J. Q. Zhou, Z. Liu, B. Ying, W. Kim, A. J. Schmitz, T. Lei, S. C. Horvath, A. J. Sturtz, K. M. McIntire, B. Evavold, F. Han, S. M. Scheaffer, I. F. Fox, , A. H. Ellebedy

This study shows that SARS-CoV-2 boosting induces GC B cell responses and that Omicron-based vaccines can elicit novel epitope-specific antibodies despite antigenic imprinting.

Nature · Apr 3, 2023Peer-reviewedImmunology

Highly Thermotolerant SARS-CoV-2 Vaccine Elicits Neutralising Antibodies Against Delta and Omicron in Mice

P. Jansen van Vuren, A. J. McAuley, M. J. Kuiper, N. B. Singanallur, M. P. Bruce, S. Riddell, S. Goldie, S. Mangalaganesh, S. Chahal, T. W. Drew, K. R. Blasdell, M. Tachedjian, L. Caly, J. D. Druce, S. Ahmed, , S. S. Vasan

This study evaluates a highly thermotolerant SARS-CoV-2 vaccine in mice, showing it elicits neutralizing antibodies against Delta and Omicron variants.

bioRxiv · Mar 3, 2022Immunology

Immunogenicity and protective efficacy of a highly thermotolerant, trimeric SARS-CoV-2 receptor binding domain derivative

S. K. Malladi, U. R. Patel, R. S. Rajmani, R. Singh, S. Pandey, S. Kumar, S. Khaleeq, P. J. v. Vuren, S. S. Riddell, S. Goldie, S. Gayathri, D. Chakraborty, P. Kalita, I. Pramanick, N. Agarwal, , R. Varadarajan

This study designs a thermotolerant trimeric RBD vaccine candidate that elicits strong neutralizing antibodies against multiple SARS-CoV-2 variants in animal models.

bioRxiv · Jan 13, 2021Microbiology

Design of a highly thermotolerant, immunogenic SARS-CoV-2 spike fragment

S. K. Malladi, R. Singh, S. Pandey, S. Gayathri, K. Kanjo, S. Ahmed, M. S. Khan, P. Kalita, N. Girish, A. Upadhyaya, P. Reddy, I. Pramanick, M. Bhasin, S. Mani, S. Bhattacharyya, , R. Varadarajan

This paper designs a thermotolerant, immunogenic SARS-CoV-2 RBD protein fragment that is stable at high temperatures and elicits neutralizing antibodies in guinea pigs.

bioRxiv · Aug 15, 2020Biophysics