Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
S. Klute, R. Nchioua, A. Cordsmeier, J. Vishwakarma, L. Koepke, H. Alshammary, C. Jung, M. Hirschenberger, H. Hoenigsperger, J.-R. Fischer, F. Zech, S. Stenger, R. Serra-Moreno, A. S. Gonzalez-Reiche, E. M. Sordillo, , K. M. Sparrer
The paper shows that the T9I mutation in the SARS-CoV-2 E protein confers autophagy resistance in Omicron variants, contributing to their spread.
bioRxiv · Apr 23, 2024 · PreprintMicrobiology
R. Nchioua, A. Schundner, S. Klute, S. Noettger, F. Zech, L. Koepke, A. Graf, S. Krebs, H. Blum, D. Kmiec, M. Frick, F. Kirchhoff, K. Sparrer
This study examines IFN sensitivity of SARS-CoV-2 variants, finding Delta remains as sensitive as early isolates, while Alpha, Beta, and Gamma show increased resistance.
bioRxiv · Nov 16, 2021Microbiology
M. Hayn, M. Hirschenberger, L. Koepke, J. H. Straub, R. Nchioua, M. H. Christensen, S. Klute, C. Prelli Bozzo, W. Aftab, F. Zech, C. Conzelmann, J. A. Mueller, S. Srinivasachar Badarinarayan, C. M. Stuerzel, I. Forne, , K. M. J. Sparrer
This study identifies SARS-CoV-2's vulnerability to IFN-γ and -λ due to its inefficient antagonism of type I and II IFN responses, suggesting potential therapeutic strategies.
bioRxiv · Oct 15, 2020Microbiology
L. Wettstein, C. Conzelmann, J. A. Mueller, T. Weil, R. Gross, M. Hirschenberger, A. Seidel, S. Klute, c. Prelli-Bozzo, F. Zech, N. Preising, G. Fois, R. Lochbaum, P. Knaff, V. Mailaender, , J. Muench
The paper identifies 1-antitrypsin as a specific inhibitor of SARS-CoV-2, showing it blocks viral infection of human airway epithelium at physiological concentrations.
bioRxiv · Jul 2, 2020 · PreprintMicrobiology