Author

W. Aftab

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Imhof· 3 shared I. Forne· 2 shared A. Lukacs· 1 shared A. Mayerhofer· 1 shared A. S. Holehouse· 1 shared A. Schmid· 1 shared A. Venkateswaran Venkatasubramani· 1 shared A. W. Thomae· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersBiochemistry

A. Imhof

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Sequence- and chemical specificity define the functional landscape of intrinsically disordered regions

I. Langstein-Skora, A. Schmid, F. Huth, D. Shabani, L. Spechtenhauser, M. Likhodeeva, F. Kunert, F. J. Metzner, R. J. Emenecker, M. O. G. Richardson, W. Aftab, M. J. Goetz, S. K. Payer, N. Pietrantoni, V. Sjenicic, , A. S. Holehouse

The paper investigates how sequence- and chemical specificity enable functional IDR diversity despite poor sequence conservation.

bioRxiv · Feb 10, 2022Biophysics

The Integrity of the Speciation Core Complex is necessary for centromeric binding and reproductive isolation in Drosophila

A. Lukacs, A. W. Thomae, P. Krueger, T. Schauer, A. Venkateswaran Venkatasubramani, N. Y. Kochanova, W. Aftab, R. Choudhury, I. Forne, A. Imhof

This study identifies a six-subunit Speciation Core Complex containing Hmr and Lhr, showing Hmr's role in centromeric binding and hybrid male lethality in Drosophila.

bioRxiv · Feb 5, 2021Biochemistry

Imperfect innate immune antagonism renders SARS-CoV-2 vulnerable towards IFN-γ and -{lambda}

M. Hayn, M. Hirschenberger, L. Koepke, J. H. Straub, R. Nchioua, M. H. Christensen, S. Klute, C. Prelli Bozzo, W. Aftab, F. Zech, C. Conzelmann, J. A. Mueller, S. Srinivasachar Badarinarayan, C. M. Stuerzel, I. Forne, , K. M. J. Sparrer

This study identifies SARS-CoV-2's vulnerability to IFN-γ and -λ due to its inefficient antagonism of type I and II IFN responses, suggesting potential therapeutic strategies.

bioRxiv · Oct 15, 2020Microbiology

Imaging mass spectrometry and shotgun proteomics reveal dysregulated pathways in male infertility

S. Lahiri, L. Valenta, W. Aftab, L. Strauss, M. Poutanen, A. Mayerhofer, A. Imhof

The paper uses proteomics and imaging mass spectrometry to identify dysregulated pathways in a mouse model of male infertility.

bioRxiv · Feb 3, 2020 · PreprintBiochemistry