Author

S. Lara-Reyna

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. R. Clark· 1 shared C. S. Martin· 1 shared C. Wong· 1 shared D. Peckham· 1 shared F. Martinon· 1 shared H. H. Jarosz-Griffiths· 1 shared J. D. O'Neil· 1 shared J. Holbrook· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

A. R. Clark

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2 papers

Recent·Most cited

The glucocorticoid dexamethasone impairs the expression of anti-viral mediators in activated macrophages by inhibiting both expression and function of interferon beta.

J. D. O'Neil, O. O. Bolimowska, S. A. Clayton, T. Tang, K. K. Daley, S. Lara-Reyna, J. Warner, C. S. Martin, R. Y. Mahida, R. S. Hardy, S. Arthur, A. R. Clark

This study shows dexamethasone inhibits antiviral gene expression in macrophages by suppressing IFNβ expression and downstream interferon-regulated genes.

bioRxiv · May 3, 2023 · PreprintImmunology

Excessive ENaC-mediated sodium influx drives NLRP3 inflammasome-dependent autoinflammation in Cystic Fibrosis

T. Scambler, H. H. Jarosz-Griffiths, S. Lara-Reyna, S. Pathak, C. Wong, J. Holbrook, F. Martinon, S. Savic, D. Peckham, M. F. McDermott

This study shows that excessive ENaC-mediated sodium influx drives NLRP3 inflammasome-dependent autoinflammation in Cystic Fibrosis, with potential therapeutic implications for lung inflammation.

bioRxiv · Nov 6, 2018 · PreprintImmunology