Author

S. Leimkuehler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

B. Nijagal· 1 shared B. Z. Zhang· 1 shared C.-S. M. Ang· 1 shared D. Stojanovski· 1 shared I. Nikolic· 1 shared J. Trapani· 1 shared K. J. Simpson· 1 shared K. M. Fujihara· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

B. Nijagal

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1 paper

Recent·Most cited

Genome-wide CRISPR screens reveal APR-246 (Eprenetapopt) triggers ferroptosis and inhibits iron-sulfur cluster biogenesis

K. M. Fujihara, B. Z. Zhang, T. D. Jackson, B. Nijagal, C.-S. M. Ang, I. Nikolic, V. Sutton, J. Trapani, K. J. Simpson, D. Stojanovski, S. Leimkuehler, S. Haupt, W. A. Phillips, N. J. Clemons

This paper identifies APR-246's mechanism of inducing ferroptosis and inhibiting iron-sulfur cluster biogenesis through cysteine conjugation in mutant-p53 cancer cells.

bioRxiv · Nov 29, 2020 · PreprintCancer Biology