S. Lin

This study shows that the SIK3 inhibitor YKL-05-099 suppresses MEF2C function and slows AML progression in mouse models.

This paper develops a tissue clearing coupled with light sheet fluorescence microscopy method to image coral holobionts at single-cell resolution, revealing endosymbiont distribution and physiological dynamics.

This study investigates transcriptomic responses of Symbiodinium kawagutii to thermal stress, phosphate deprivation, and glycerol-3-phosphate replacement, identifying core genes and differentially expressed genes across conditions.

This study shows that vimentin intermediate filaments provide cytoplasmic mechanics that enhance strength, stretchability, resilience, and toughness under severe deformations.

This paper improves L-asparaginase therapeutic efficiency through site-specific PEGylation of subunits, increasing molecular weight and extending half-life without compromising catalytic activity.

The paper constructs a lung cancer database with gene expression and clinical data from 6,700 patients and develops an open web portal for data exploration and analysis.

This study shows that the FACT complex facilitates DME-mediated DNA demethylation at heterochromatin during Arabidopsis reproduction by enabling access to GC-rich, nucleosome-dense regions.