Author

Y. Tarumoto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Organism:multiple species· 1

Frequent Co-Authors

C. R. Vakoc· 2 shared A. Kentsis· 1 shared A. Makino· 1 shared B. I. Leach· 1 shared B. J. Diaz· 1 shared C. Chen· 1 shared C. Vakoc· 1 shared E. M. Schatoff· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

C. R. Vakoc

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Genome-scale CRISPR-Cas9 screen identifies novel host factors as potential therapeutic targets for SARS-CoV-2 infection.

M. Sakai, Y. Masuda, Y. Tarumoto, N. Aihara, Y. Tsunoda, M. Iwata, Y. Kamiya, R. Komorizono, T. Noda, K. Yusa, K. Tomonaga, A. Makino

The paper identifies TRIM28, TRIM33, EHMT1, and EHMT2 as novel host factors involved in SARS-CoV-2 infection and shows that EHMT1/2 inhibition reduces viral growth and disease severity.

bioRxiv · Mar 6, 2023Microbiology

Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia

S. Takao, L. Forbes, M. Uni, S. Cheng, J. M. B. Pineda, Y. Tarumoto, P. Cifani, G. Minuesa, C. Chen, M. G. Kharas, R. K. Bradley, C. R. Vakoc, R. P. Koche, A. Kentsis

This study identifies aberrant MYB complex assembly as a driver of oncogenic gene expression in AML and shows that targeting this complex can induce differentiation and apoptosis.

bioRxiv · May 5, 2020Cancer Biology

Tankyrase inhibition sensitizes cells to CDK4 blockade

M. Foronda, Y. Tarumoto, E. M. Schatoff, B. I. Leach, B. J. Diaz, S. Goswami, M. Shusterman, C. R. Vakoc, L. Dow

This study identifies that combining TNKS inhibition with CDK4 loss drives G1 cell cycle arrest and senescence in epithelial cancers.

bioRxiv · Jun 21, 2019Cancer Biology

The Salt-Inducible Kinase inhibitor YKL-05-099 suppresses MEF2C function and acute myeloid leukemia progression in vivo

Y. Tarumoto, S. Lin, J. Wang, J. Milazzo, Y. Xu, N. Gray, K. Stegmaier, C. Vakoc

This study shows that the SIK3 inhibitor YKL-05-099 suppresses MEF2C function and slows AML progression in mouse models.

bioRxiv · May 14, 2019 · PreprintCancer Biology