Author

D. Christensen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 5 Research Focus:cell type annotation· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:proteomics· 2

Frequent Co-Authors

F. Follmann· 2 shared G. K. Pedersen· 2 shared A. L. Coelho· 1 shared A. L. Sangster· 1 shared A. Lim· 1 shared A. Price· 1 shared A. Straily· 1 shared A. Uehara· 1 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersImmunology

F. Follmann

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Protection against experimental cryptococcosis elicited by Cationic Adjuvant Formulation 01-adjuvanted subunit vaccines

R. Wang, L. V. N. Oliveira, M. M. Hester, D. M. Carlson, D. Christensen, C. A. Specht, S. M. Levitz

This paper develops multivalent cryptococcal vaccines using CAF01 adjuvant that protect mice from experimental cryptococcosis by inducing IFNγ and IL-17 responses.

bioRxiv · Apr 24, 2024 · PreprintImmunology

Caveolin scaffolding domain (CSD) peptide LTI-2355 modulates the phagocytic and synthetic activity of lung derived myeloid cells in Idiopathic Pulmonary Fibrosis (IPF) and Post-acute sequelae of COVID-fibrosis (PASC-F)

B. Creyns, B. MacKenzie, Y. Sa, A. L. Coelho, D. Christensen, T. Parimon, B. Windsor, C. M. Hogaboam

This study shows that the CSD peptide LTI-2355 improves phagocytic and reduces pro-inflammatory activity in myeloid cells from IPF and PASC-F patients.

bioRxiv · Dec 1, 2023Immunology

A novel adjuvant formulation induces robust Th1/Th17 memory and mucosal recall responses in Non-Human Primates

J. S. Woodworth, V. Contreras, D. Christensen, T. Naninck, N. Kahlaoui, A.-s. Gallouët, S. Langlois, E. Burban, C. Joly, W. Gros, N. Bosquet, J. Morin, M. L. Olsen, I. Rosenkrands, A.-K. Stein, , R. Mortensen

This paper develops a novel liposomal adjuvant, CAF(R)10b, that induces robust Th1/Th17 memory and mucosal recall responses in non-human primates.

bioRxiv · Feb 23, 2023 · PreprintImmunology

HIV-1 preintegration complex preferentially integrates the viral DNA into nucleosomes containing trimethylated histone 3-lysine 36 modification

N. E. Sapp, N. Burge, K. Cox, S. Thapa, P. Prakash, M. Balasubramaniam, D. Christensen, M. Li, J. Linderberger, M. Kvaratskhelia, W. I. Sundquist, J. Pandhare, R. Craigie, M. G. Poirier, C. Dash

This study identifies that HIV-1 preintegration complex preferentially integrates viral DNA into nucleosomes with H3K36me3 modification and linker DNA.

bioRxiv · Feb 16, 2022 · PreprintBiochemistry

A novel Pan-viral prophylaxis strategy using vaccine adjuvant CAF09b protects against influenza virus infection

J. Zimmermann, S. T. Schmidt, R. Trebbien, R. J. Cox, F. Zhou, F. Follmann, G. K. Pedersen, D. Christensen

This study shows that the adjuvant CAF09b can protect mice from influenza infection when administered before viral exposure but not after.

bioRxiv · Oct 21, 2021 · PreprintImmunology

IL-4 and helminth infection downregulate MINCLE-dependent macrophage response to mycobacteria and Th17 adjuvanticity

R. Lang, S. Wirtz, D. Voehringer, M. Lacorcia, M. Altunay, B. Bodendorfer, C. Schubart, D. Christensen, C. Alexander, J. Schick, C. P. da Costa

This study shows IL-4 and helminth infection reduce MINCLE expression on macrophages, impairing Th17 responses to MINCLE-based vaccines.

bioRxiv · Aug 17, 2021Immunology

One Health Investigation of SARS-CoV-2 Infection and Seropositivity among Pets in Households with Confirmed Human COVID-19 Cases - Utah and Wisconsin, 2020

G. W. Goryoka, C. M. Cossaboom, R. Gharpure, P. Dawson, C. Tansey, J. Rossow, V. Mrotz, J. Rooney, M. Torchetti, C. M. Loiacono, M. L. Killian, M. Jenkins-Moore, A. Lim, K. Poulsen, D. Christensen, , C. Barton Behravesh

This study investigates SARS-CoV-2 infection and seropositivity in pets from households with confirmed human COVID-19 cases, finding that 17% of pets had neutralizing antibodies and suggesting transmission from humans to pets.

bioRxiv · Apr 11, 2021Microbiology