Author

S. McGraw

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

C. Beausejour· 2 shared D. Sinnett· 2 shared M. Caron· 2 shared V. Bertrand-Lehouillier· 2 shared A. Beaudry· 1 shared A. Deprez· 1 shared A. Haman· 1 shared A. Lemieux· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

C. Beausejour

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Rescuing DNMT1 Fails to Fully Reverse the Molecular and Functional Repercussions of Its Loss in Mouse Embryonic Stem Cells

E. Elder, A. Lemieux, L.-M. Legault, M. Caron, V. Bertrand-Lehouillier, T. Dupas, N. J.-M. Raynal, G. Bourque, D. Sinnett, N. Gevry, S. McGraw

This paper investigates whether rescuing DNMT1 activity can reverse its loss in mouse embryonic stem cells, finding only partial reversal with lasting effects on epigenetic landscapes and cellular function.

bioRxiv · May 7, 2024Cell Biology

Clearance of defective muscle stem cells by senolytics reduces the expression of senescence-associated secretory phenotype and restores myogenesis in myotonic dystrophy type 1.

T. Conte, G. D. Bishop, Z. Orfi, I. Mokhtari, A. Deprez, M.-P. Roussel, I. Cote, O. Pellerito, D. Maggiorani, B. Benabdallah, S. Leclerc, L. Feulner, J. Mathieu, C. Gagnon, G. Andelfinger, , N. Dumont

This study identifies a senescent molecular signature in DM1 myogenic cells and shows that senolytics reduce SASP and restore myogenesis.

bioRxiv · Jun 22, 2022 · PreprintCell Biology

Targeting MYC Overexpressing Leukemia with Cardiac Glycoside Proscillaridin Through Downregulation of Histone Acetyltransferases

E. M. Da Costa, G. Armaos, G. McInnes, A. Beaudry, G. Moquin-Beaudry, V. Bertrand-Lehouillier, M. Caron, C. Richer, P. St-Onge, J. Johnson, N. Krogan, Y. Sai, M. Downey, M. Rafei, M. Boileau, , N. J. M. Raynal

This study shows proscillaridin, a cardiac glycoside, selectively targets MYC overexpressing leukemia by downregulating histone acetyltransferases and inducing hematopoietic differentiation.

bioRxiv · Dec 11, 2018 · PreprintPharmacology & Toxicology