Author

K. Tandoc

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

I. Topisirovic· 3 shared L. Lee· 2 shared L.-M. Postovit· 2 shared M. Jewer· 2 shared O. Larsson· 2 shared A. Brumwell· 1 shared A. Koromilas· 1 shared A. Saric· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersCancer Biology

I. Topisirovic

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Epigenetic coordination of transcriptional and translational programs in hypoxia

K. Watt, B. Dauber, K. J. Szkop, L. Lee, P. Jovanovic, S. Chen, R. Palia, J. A. Vassalakis, T. T. Cooper, D. Papadopoli, L. Masvidal, M. Jewer, K. Tandoc, H. Plummer, G. A. Lajoie, , L.-M. Postovit

The paper shows hypoxia induces TSS switching via H3K4me3 changes, altering translation of key metabolic genes like PDK1.

bioRxiv · Sep 16, 2023 · PreprintCancer Biology

Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activation

V. E. B. Hipolito, J. Diaz, K. Tandoc, C. Oertlin, J. Ristau, N. Chauhan, A. Saric, S. McLaughlan, O. Larsson, I. Topisirovic, R. Botelho

This study identifies mTORC1-dependent translation as a mechanism for endo-lysosome expansion and antigen presentation during phagocyte activation.

bioRxiv · Nov 13, 2019Cell Biology

Translational control of breast cancer plasticity

M. Jewer, L. Lee, G. Zhang, J. Liu, S. D. Findlay, K. M. Vincent, K. Tandoc, D. Dieters-Castator, D. F. Quail, I. Dutta, M. Coatham, Z. Xu, B.-J. Guan, M. Hatzoglou, A. Brumwell, , L.-M. Postovit

The paper identifies hypoxia and drug-induced translational activation of NANOG, SNAIL, and NODAL isoforms that drive breast cancer plasticity and stem-cell-like phenotypes, with potential therapeutic implications.

bioRxiv · Apr 2, 2019Cancer Biology