Author

S. Nayar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Assay:scRNA-seq· 4 Research Focus:cell-cell communication· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Approach:statistical model· 3 Approach:deep learning· 2

Frequent Co-Authors

A. Filer· 2 shared F. Barone· 2 shared M. Giri· 2 shared A. Alshayea· 1 shared A. F. Cunningham· 1 shared A. Greenstein· 1 shared A. Jainarayanan· 1 shared A. Jonsson· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersImmunology

A. Filer

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A longitudinal single-cell therapeutic atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease

T. Thomas, C. Rich-Griffin, M. Pohin, M. Friedrich, D. Aschenbrenner, J. Pakpoor, A. Jainarayanan, A.-I. Voda, R. Sanches Peres, E. Nee, D. Sathananthan, D. Kotliar, J. Turner, S. Nayar, F. Zhang, , C. Buckley

This study creates a therapeutic atlas of anti-TNF treatment in IBD, showing disease- and therapy-specific cellular changes and identifying IFN signalling as a potential target for JAK inhibition.

bioRxiv · May 5, 2023Immunology

Salmonella infection induces the reorganisation of follicular dendritic cell networks concomitant with the failure to generate germinal centres

E. Marcial-Juarez, M. Perez-Toledo, S. Nayar, E. Pipi, A. Alshayea, R. Persaud, S. E. Jossi, R. Lamerton, F. Barone, I. R. Henderson, A. F. Cunningham

This study shows that Salmonella infection disrupts follicular dendritic cell networks and prevents germinal center formation in the spleen.

iScience · Apr 1, 2023Peer-reviewedImmunology

A cellular and spatial map of salivary glands at single cell resolution reveals the functional basis of tertiary lymphoid structure formation in Sjogren's syndrome

S. Nayar, J. D. Turner, S. Asam, E. Fennell, M. Pugh, S. Colafrancesco, O. Berardicurti, C. G. Smith, J. Flint, A. Teodosio, V. Iannizzotto, D. G. Gardner, J. v. Roon, I. Korsunsky, Roche Fibroblast Network Consortium, , F. Barone

This study maps cellular and spatial features of tertiary lymphoid structures in human salivary glands at single-cell resolution, identifying novel cell states and their roles in TLS formation.

bioRxiv · Nov 3, 2022 · PreprintImmunology

Single-cell transcriptomic profiling of healthy and fibrotic adult zebrafish liver reveals conserved cell identities and stellate cell activation phenotypes with human liver

J. K. Morrison, C. DeRossi, I. L. Alter, S. Nayar, M. Giri, C. Zhang, J. H. Cho, J. Chu

This study uses scRNA-seq to compare healthy and fibrotic adult zebrafish liver with human liver, identifying conserved cell identities and fibrosis-related gene expression patterns.

bioRxiv · Aug 6, 2021 · PreprintCell Biology

Single-cell analysis of Crohn’s disease lesions identifies a pathogenic cellular module associated with resistance to anti-TNF therapy

J. C. Martin, G. Boschetti, C. Chang, R. Ungaro, M. Giri, L.-S. Chuang, S. Nayar, A. Greenstein, M. Dubinsky, L. Walker, A. Leader, J. Fine, C. Whitehurst, L. Mbow, S. Kugathasan, , E. Kenigsberg

bioRxiv · Dec 20, 2018Immunology