Author

M. Pohin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

M. Friedrich· 4 shared F. Powrie· 3 shared R. Sanches Peres· 2 shared S. Raychaudhuri· 2 shared T. Thomas· 2 shared A. Bertocchi· 1 shared A. Easton· 1 shared A. Filer· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersImmunology

M. Friedrich

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4 papers

Recent·Most cited

A longitudinal single-cell therapeutic atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease

T. Thomas, C. Rich-Griffin, M. Pohin, M. Friedrich, D. Aschenbrenner, J. Pakpoor, A. Jainarayanan, A.-I. Voda, R. Sanches Peres, E. Nee, D. Sathananthan, D. Kotliar, J. Turner, S. Nayar, F. Zhang, , C. Buckley

This study creates a therapeutic atlas of anti-TNF treatment in IBD, showing disease- and therapy-specific cellular changes and identifying IFN signalling as a potential target for JAK inhibition.

bioRxiv · May 5, 2023Immunology

MHC class II antigen presentation by intestinal epithelial cells fine-tunes bacteria-reactive CD4 T cell responses

C. Heuberger, A. Janney, N. Ilott, A. Bertocchi, S. Pott, Y. Gu, M. Pohin, M. Friedrich, E. Mann, C. Pearson, F. Powrie, J. Pott, E. E. Thornton, K. J. Maloy

This study shows that intestinal epithelial cells expressing MHC II modulate CD4 T cell responses during intestinal inflammation, dampening pro-inflammatory effector Th cells.

bioRxiv · Jan 23, 2023Immunology

Adipocyte autophagy limits gut inflammation by controlling oxylipin levels

F. C. Richter, M. Friedrich, N. Kampschulte, M. Pohin, G. Alsaleh, I. Guschina, S. K. Wideman, E. Johnson, M. Borsa, K. Piletic, P. Hahn, H. S. Schipper, C. Edwards, R. Zechner, N. H. Schebb, , A. K. Simon

The paper shows that adipocyte autophagy reduces gut inflammation by regulating oxylipin levels through NRF2-mediated Ephx1 upregulation.

bioRxiv · Oct 25, 2021Immunology

IL-1-driven stromal-neutrophil interaction in deep ulcers defines a pathotype of therapy non-responsive inflammatory bowel disease

M. Friedrich, M. Pohin, M. A. Jackson, I. Korsunsky, S. Bullers, K. Rue-Albrecht, Z. Christoforidou, D. Santhananthan, R. Ravindran, R. Sanches Peres, H. Sharpe, K. Wei, G. F. M. Watts, E. H. Mann, A. Geremia, , F. M. Powrie

bioRxiv · Feb 5, 2021 · PreprintImmunology