Author

E. Kenigsberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Organism:human· 5 Research Focus:cell-cell communication· 4 Research Focus:differential expression· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

M. Merad· 5 shared A. Tabachnikova· 4 shared C. Chang· 4 shared S. Gnjatic· 4 shared A. H. Rahman· 3 shared J. C. Martin· 3 shared J. LeBerichel· 3 shared L. Walker· 3 shared

Activity by Year

2018-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersImmunology

M. Merad

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Intratumoral mregDC and CXCL13 T helper niches enable local differentiation of CD8 T cells following PD-1 blockade

A. Magen, P. Hamon, N. Fiaschi, L. Troncoso, E. Humblin, D. D'souza, T. Dawson, M. D. Park, J. Kim, S. Hamel, M. Buckup, C. Chang, A. Tabachnikova, H. Schwartz, N. Malissen, , Merad

The paper identifies intratumoral niches involving mregDC and CXCL13+ Th cells that support CD8 T cell differentiation following PD-1 blockade in HCC patients.

bioRxiv · Jun 22, 2022 · PreprintImmunology

Spatial positioning and matrix programs of cancer-associated fibroblasts promote T cell exclusion in human lung tumors

J. A. Grout, P. Sirven, A. M. Leader, S. Maskey, E. Hector, I. Puisieux, F. Steffan, E. Cheng, N. Tung, M. Maurin, R. Vaineau, L. Karpf, M. Plaud, M. Casanova-Acebes, A. Tabachnikova, , H. Salmon

The paper identifies two CAF subsets in human lung tumors that promote T cell exclusion through distinct matrix programs and spatial organization.

bioRxiv · Jan 20, 2022Cancer Biology

Shift of lung macrophage composition is associated with COVID-19 disease severity and recovery

S. T. Chen, M. D. Park, D. M. Del Valle, M. Buckup, A. Tabachnikova, N. W. Simons, K. Mouskas, B. Lee, D. Geanon, D. D'Souza, T. Dawson, R. Marvin, K. Nie, R. Thompson, Z. Zhao, , M. Merad

This study identifies shifts in lung macrophage composition linked to COVID-19 severity and recovery, suggesting therapeutic strategies targeting macrophage function.

bioRxiv · Jan 11, 2022 · PreprintImmunology

CITEseq analysis of non-small-cell lung cancer lesions reveals an axis of immune cell activation associated with tumor antigen load and TP53 mutations

A. M. Leader, J. A. Grout, C. Chang, B. Maier, A. Tabachnikova, L. Walker, A. Lansky, J. LeBerichel, N. Malissen, M. Davila, J. Martin, G. Magri, K. Tuballes, Z. Zhoa, F. Petralia, , M. Merad

The paper analyzes CITEseq data from NSCLC lesions to identify an immune cell activation module linked to tumor antigen load and TP53 mutations.

bioRxiv · Jul 16, 2020 · PreprintImmunology

Serum Amyloid A Proteins Induce Pathogenic TH17 Cells and Promote Inflammatory Disease

J.-Y. Lee, J. A. Hall, L. Kroehling, L. Wu, T. Najar, H. H. Nguyen, W.-Y. Lin, S. T. Yeung, H. M. Silva, D. Li, A. Hine, P. Loke, D. Hudesman, J. C. Martin, E. Kenigsberg, , D. R. Littman

This study shows serum amyloid A proteins drive pathogenic TH17 cell differentiation and promote inflammatory disease through STAT3-activating cytokines.

bioRxiv · Jun 25, 2019Immunology

Single-cell analysis of Crohn’s disease lesions identifies a pathogenic cellular module associated with resistance to anti-TNF therapy

J. C. Martin, G. Boschetti, C. Chang, R. Ungaro, M. Giri, L.-S. Chuang, S. Nayar, A. Greenstein, M. Dubinsky, L. Walker, A. Leader, J. Fine, C. Whitehurst, L. Mbow, S. Kugathasan, , E. Kenigsberg

bioRxiv · Dec 20, 2018Immunology