Author

C. G. Smith

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:variant calling· 3 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1

Frequent Co-Authors

D. Gale· 3 shared I. Hudecova· 3 shared J. C. Wan· 3 shared K. Heider· 3 shared N. Rosenfeld· 3 shared W. N. Cooper· 3 shared D. Chandrananda· 2 shared F. Mouliere· 2 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

D. Gale

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A cellular and spatial map of salivary glands at single cell resolution reveals the functional basis of tertiary lymphoid structure formation in Sjogren's syndrome

S. Nayar, J. D. Turner, S. Asam, E. Fennell, M. Pugh, S. Colafrancesco, O. Berardicurti, C. G. Smith, J. Flint, A. Teodosio, V. Iannizzotto, D. G. Gardner, J. v. Roon, I. Korsunsky, Roche Fibroblast Network Consortium, , F. Barone

This study maps cellular and spatial features of tertiary lymphoid structures in human salivary glands at single-cell resolution, identifying novel cell states and their roles in TLS formation.

bioRxiv · Nov 3, 2022 · PreprintImmunology

Gulf of Mexico blue hole harbors high levels of novel microbial lineages

N. V. Patin, Z. A. Dietrich, A. Stancil, M. Quinan, J. Beckler, E. R. Hall, J. Culter, C. G. Smith, M. Taillefert, F. J. Stewart

The paper characterizes microbial communities in a Gulf of Mexico blue hole, revealing novel taxa and metabolic capabilities in hypoxic and anoxic zones.

bioRxiv · Oct 18, 2020Microbiology

High-sensitivity monitoring of ctDNA by patient-specific sequencing panels and integration of variant reads

J. C. Wan, K. Heider, D. Gale, S. Murphy, E. Fisher, J. Morris, F. Mouliere, D. Chandrananda, A. Marshall, A. B. Gill, P. Y. Chan, E. Barker, G. Young, W. N. Cooper, I. Hudecova, , N. Rosenfeld

This paper introduces INVAR, a method to improve ctDNA detection sensitivity using patient-specific sequencing panels and variant read integration, achieving ppm-level detection in clinical samples.

bioRxiv · Sep 11, 2019 · PreprintCancer Biology

Comprehensive characterisation of cell-free tumour DNA in plasma and urine of patients with renal tumours

C. G. Smith, T. Moser, J. Burge, M. Eldridge, A. L. Riediger, F. Mouliere, D. Chandrananda, K. Heider, J. C. Wan, A. Y. Warren, J. Morris, I. Hudecova, W. N. Cooper, T. J. Mitchell, D. Gale, , G. D. Stewart

The paper uses sequencing methods to show that cell-free tumour DNA levels are low in renal cancer but can still be informative with improved detection strategies.

bioRxiv · Sep 11, 2019 · PreprintCancer Biology

Detection of ctDNA from dried blood spots after DNA size selection

K. Heider, J. C. Wan, J. Hall, S. Boyle, I. Hudecova, D. Gale, W. N. Cooper, P. G. Corrie, J. D. Brenton, C. G. Smith, N. Rosenfeld

This paper develops a protocol to detect ctDNA from dried blood spots using low-depth WGS and fragment size selection, showing its feasibility in human and mouse models.

bioRxiv · Sep 5, 2019Cancer Biology