S. O. Rizzoli

Doubling the resolution of fluorescence-lifetime single-molecule localization microscopy with image scanning microscopy

This paper combines FL-SMLM with ISM to improve lateral localization accuracy and eliminate chromatic aberration in single-molecule imaging.

Age-dependent structural reorganization of utricular ribbon synapses

This study examines age-related structural changes in utricular ribbon synapses in mice, finding age-dependent formation of floating ribbon clusters in type I vestibular hair cells.

Heat denaturation enables multicolor X10-STED microscopy at single-digit nanometer resolution

This paper introduces X10ht, a method that enables multicolor STED microscopy at 6-8 nm resolution by expanding biological samples 10-fold through high-temperature homogenization.

Protein nanobarcodes enable single-step multiplexed fluorescence imaging

This paper introduces protein nanobarcodes for single-step multiplexed fluorescence imaging, enabling precise analysis of protein combinations.

Local translation in synaptic mitochondria influences synaptic transmission

The paper uses an imaging approach to study mitochondrial translation in neurons, finding it occurs in dendrites and axons, correlates with synaptic activity, and affects synaptic function.

Circumvention of common labeling artifacts using secondary nanobodies

This paper demonstrates that monovalent nanobodies improve imaging accuracy and reduce artifacts compared to traditional secondary antibodies in super-resolution microscopy.

X10 Expansion Microscopy Enables 25 nm Resolution on Conventional Microscopes

This paper introduces X10 expansion microscopy, achieving 25-30 nm resolution on conventional microscopes by improving the gel recipe for a 10x expansion factor.