T. Moser

CryoRhodopsins: a comprehensive characterization of a group of microbial rhodopsins from cold environments

The paper characterizes CryoRhodopsins from cold environments, revealing their dual functionality and structural adaptations to low temperatures.

Efficient and sustained optogenetic control of sensory and cardiac systems

This paper introduces ChReef, an improved optogenetic tool with enhanced performance in sensory and cardiac systems, demonstrating its effectiveness in restoring visual and auditory function.

Visualizing proteins by expansion microscopy

This paper introduces ONE microscopy, a technique that enables nanoscale imaging of single proteins and molecular complexes, revealing structural details in cells and disease samples.

Cryo-EM structure of the diapause chaperone artemin

The paper reports the cryo-EM structure of artemin, revealing its intramolecular disulfide bond and C-terminal helix's role in dimer stabilization.

The mammalian rod synaptic ribbon is essential for Cav channel facilitation and ultrafast fusion of the readily releasable pool of vesicles

This study shows that the synaptic ribbon in rod photoreceptors facilitates Cav channel opening and increases the size of the readily releasable pool of synaptic vesicles, essential for rapid glutamate release.

Circumvention of common labeling artifacts using secondary nanobodies

This paper demonstrates that monovalent nanobodies improve imaging accuracy and reduce artifacts compared to traditional secondary antibodies in super-resolution microscopy.

Comprehensive characterisation of cell-free tumour DNA in plasma and urine of patients with renal tumours

The paper uses sequencing methods to show that cell-free tumour DNA levels are low in renal cancer but can still be informative with improved detection strategies.

Inference of tumor cell-specific transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection of cancer

This study infers tumor cell-specific transcription factor binding from cell-free DNA to predict tumor subtypes and detect cancer early.