Author

S. O. Vargas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. Alsuraimi· 1 shared A. B. Waxman· 1 shared A. C. Straub· 1 shared A. Dosunmu-Ogunbi· 1 shared A. Gorelova· 1 shared A. J. McAdam· 1 shared A. J. Poret· 1 shared A. Mora· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

A. Alsuraimi

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Author profile →

2 papers

Recent·Most cited

De novo mutations mediate phenotypic switching in an opportunistic human lung pathogen

A. J. Poret, M. M. Schaefers, C. Merakou, K. E. Mansour, G. K. Lagoudas, A. R. Cross, J. B. Goldberg, R. Kishony, A. Z. Uluer, A. J. McAdam, P. C. Blainey, S. O. Vargas, T. D. Lieberman, G. P. Priebe

This study shows that de novo mutations in Burkholderia dolosa cause phenotypic switching, with O-antigen loss increasing immune cell uptake but reducing lung competitiveness, depending on infection duration and tissue localization.

bioRxiv · Feb 6, 2024 · PreprintMicrobiology

The Role of EBP50 in Regulating Endothelial-To-Mesenchymal Transition in Pulmonary Hypertension

A. Gorelova, M. Berman, M. Sharifi-Sanjani, A. Pulgarin Rocha, A. Alsuraimi, P. Riva, V. Negi, T. Bertero, D. Goncharov, T. Kudryashova, A. Dosunmu-Ogunbi, A. Rajaratnam, L. Harvey, M. Nouraie, J. Baust, , I. Al Ghouleh

This study shows EBP50 downregulation promotes EndMT in pulmonary hypertension by increasing Snail, Zeb1, and Slug expression, and mesenchymal markers, while reducing cell proliferation and barrier function.

bioRxiv · May 31, 2022 · PreprintCell Biology