Author

S. Pomella

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

J. Khan· 2 shared R. Rota· 2 shared B. E. Gryder· 1 shared B. Gryder· 1 shared B. Schaefer· 1 shared C. R. Vakoc· 1 shared E. Y. Chen· 1 shared J. Chen· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

J. Khan

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2 papers

Recent·Most cited

SNAI2-mediated direct repression of BIM protects rhabdomyosarcoma from ionizing radiation

L. Wang, N. R. Hensch, K. Bondra, P. Sreenivas, X. R. Zhao, J. Chen, K. Baxi, R. M. Campos, B. Gryder, S. Pomella, R. Rota, E. Y. Chen, J. Khan, P. J. Houghton, M. S. Ignatius

This study identifies SNAI2 as a repressor of BIM, protecting rhabdomyosarcoma from ionizing radiation through a P53-independent mechanism.

bioRxiv · Jan 25, 2021Cancer Biology

Miswired enhancer logic drives translocation positive rhabdomyosarcoma

B. E. Gryder, M. Wachtel, K. Chang, O. E. Demerdash, N. G. Aboreden, W. Ewert, S. Pomella, W. Mohammed, R. Rota, J. S. Wei, Y. Song, B. Schaefer, C. R. Vakoc, J. Khan

The paper identifies a miswired enhancer logic driven by PAX3-FOXO1 translocation in rhabdomyosarcoma, disrupting normal transcription factor regulation and promoting undifferentiated proliferation.

bioRxiv · Sep 6, 2019 · PreprintCancer Biology