Author

S. Radford

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

E. Hewitt· 2 shared P. Actis· 2 shared A. Aksimentiev· 1 shared A. Lends· 1 shared A. Loquet· 1 shared A. Muga· 1 shared A. N. Calabrese· 1 shared C. C. Chau· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBiophysics

E. Hewitt

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3 papers

Recent·Most cited

Single molecule delivery into living cells

C. Chau, C. Maffeo, A. Aksimentiev, S. Radford, E. Hewitt, P. Actis

This paper introduces a nanoinjection platform using nanopipettes to deliver macromolecules into cells with single molecule resolution, showing phenotypic changes and enhanced detection through macromolecular crowding.

bioRxiv · Jan 9, 2024Biophysics

A targetable N-terminal motif orchestrates α-synuclein oligomer to fibril conversion

J. Santos, J. Cuellar, I. Pallares, E. J. Byrd, A. Lends, F. Moro, M. B. Abdul-Shukkoor, J. Pujols, L. Velasco-Carneros, F. Sobott, D. E. Otzen, A. N. Calabrese, A. Muga, J. S. Pedersen, A. Loquet, , S. Ventura

This study identifies an N-terminal motif in α-synuclein oligomers that drives fibril conversion and shows how a mutation disrupts this process, offering a new therapeutic target.

bioRxiv · Feb 10, 2023Biophysics

Asymmetric Ion Mobility and Interface Displacement Drive the Signal Enhancement in a Polymer-electrolyte Nanopore

F. Marcuccio, D. Soulias, C. C. Chau, S. Radford, E. Hewitt, P. Actis, M. Edwards

This study investigates how adding PEG to the external solution enhances nanopore signal detection by altering ion transport and interface displacement.

bioRxiv · Aug 17, 2022 · PreprintBiophysics