A. Loquet

CapP mediates the structural formation of biofilm-specific pili in the opportunistic human pathogen Bacillus cereus

This paper identifies BC1280 as an essential chaperone for biofilm-specific pili assembly in B. cereus, showing its role in filament formation and regulation of EPS expression.

Cyclo(Pro-Tyr) elicits conserved cellular damage in fungi by targeting the ATPase Pma1 in plasma membrane domains

This study identifies cyclo(Pro-Tyr) as a metabolite that disrupts eukaryotic cellular membranes by targeting Pma1 ATPase in microdomains, inducing oxidative stress and membrane fluidity changes in fungi and nematodes.

Molecular characterization of the N-terminal half of TasA during functional amyloid assembly and its contribution to Bacillus subtilis biofilm formation

This study investigates the N-terminal half of TasA in Bacillus subtilis, identifying sequence features critical for amyloid assembly and biofilm formation.

A targetable N-terminal motif orchestrates α-synuclein oligomer to fibril conversion

This study identifies an N-terminal motif in α-synuclein oligomers that drives fibril conversion and shows how a mutation disrupts this process, offering a new therapeutic target.

The actin depolymerizing factor StADF2 alters StREM1.3 plasma membrane nanodomains to inhibit the Potato Virus X

This study shows that StADF2 alters StREM1.3 plasma membrane nanodomains to inhibit PVX cell-to-cell movement through REMORIN-dependent mechanisms.

Driving forces behind remorin nanodomain formation in anionic lipid membranes

The paper investigates how phosphorylation of the N-terminal IDD in REM1.3 influences remorin clustering into lipid nanodomains in anionic model membranes.

Protein resonance assignment by solid-state NMR based on 1H-detected 13C-based double-quantum spectroscopy at fast MAS

This paper introduces a method using 1H-detected 13C-based double-quantum spectroscopy at fast MAS to sequentially assign resonances in insoluble proteins without requiring specific deuteration.

Structural and molecular basis of cross-seeding barriers in amyloids

This study identifies molecular determinants that prevent cross-seeding between structurally similar amyloids, revealing that side-chain positions, not just backbone structure, dictate prion specificity.

Identification of NLR-associated amyloid signaling motifs in filamentous bacteria

The paper identifies bacterial amyloid signaling motifs related to fungal and mammalian motifs and shows they form prion-like structures in fungi and in vitro.

Avidity-driven polarity establishment via multivalent lipid-GTPase module interactions

The paper identifies multivalent anionic lipid interactions as critical for establishing cellular polarity through the Cdc42 GTPase module in budding yeast.