Author

J. Cuellar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

J. M. Valpuesta· 3 shared A. Lends· 1 shared A. Loquet· 1 shared A. Makaju· 1 shared A. Martinez· 1 shared A. Muga· 1 shared A. N. Calabrese· 1 shared B. M. Willardson· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersBiochemistry

J. M. Valpuesta

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Author profile →

3 papers

Recent·Most cited

A targetable N-terminal motif orchestrates α-synuclein oligomer to fibril conversion

J. Santos, J. Cuellar, I. Pallares, E. J. Byrd, A. Lends, F. Moro, M. B. Abdul-Shukkoor, J. Pujols, L. Velasco-Carneros, F. Sobott, D. E. Otzen, A. N. Calabrese, A. Muga, J. S. Pedersen, A. Loquet, , S. Ventura

This study identifies an N-terminal motif in α-synuclein oligomers that drives fibril conversion and shows how a mutation disrupts this process, offering a new therapeutic target.

bioRxiv · Feb 10, 2023Biophysics

Molecular determinants of Arc oligomerization and formation of virus-like capsids

M. S. Eriksen, O. Nikolaienko, E. I. Hallin, S. Grodem, H. J. Bustad, M. I. Flydal, R. O'Connell, T. Hosokawa, D. Lascu, S. Akerkar, J. Cuellar, J. J. Chambers, I. Merski, G. Muruganandam, R. Loris, , C. R. Bramham

This paper identifies a 28-amino-acid region in Arc critical for oligomerization and virus-like capsid formation, showing that exogenous RNA enhances assembly.

bioRxiv · Nov 22, 2019 · PreprintBiochemistry

Molecular Architecture of the Bardet-Biedl Syndrome 2-7-9 Subcomplex

W. G. Ludlam, T. Aoba, J. Cuellar, M. T. Bueno-Carrasco, A. Makaju, J. D. Moody, S. Franklin, J. M. Valpuesta, B. M. Willardson

The paper determines the structure of a BBSome subcomplex and shows how a mutation disrupts its assembly, linking it to Bardet-Biedl syndrome.

bioRxiv · Jul 11, 2019Biochemistry