HIV-1 uncoating occurs via a series of rapid biomechanical changes in the core related to individual stages of reverse transcription
S. Rankovic, A. Deshpande, S. Harel, C. Aiken, I. Rousso
This study uses atomic force microscopy to observe stiffness changes in HIV-1 cores during reverse transcription, linking mechanical spikes to specific stages of the process.
bioRxiv · Jan 16, 2021Biophysics