Author

S. Shum

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:non-human primate· 3 Research Focus:development & morphogenesis· 2 Research Focus:host-pathogen & immune response· 2 Assay:behavioral assay· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

N. Isoherranen· 4 shared B. Crouthamel· 3 shared J. Jing· 3 shared K. S. Grant· 3 shared N. McKain· 3 shared R. Petroff· 3 shared T. M. Burbacher· 3 shared C. Stanley· 2 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersPharmacology & Toxicology

N. Isoherranen

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4 papers

Recent·Most cited

Bridging the gap between in silico and in vivo: modeling opioid disposition in a kidney proximal tubule microphysiological system

T. Imaoka, W. Huang, S. Shum, D. W. Hailey, S.-Y. Chang, A. Chapron, C. K. Yeung, J. Himmelfarb, N. Isoherranen, E. J. Kelly

This study predicts opioid kidney clearance and systemic disposition in CKD patients using a microphysiological system and PBPK modeling.

bioRxiv · Dec 4, 2020Pharmacology & Toxicology

Preclinical Modeling of Exposure to a Global Marine Bio Contaminant: Effects of In Utero Domoic Acid Exposure on Neonatal Behavior and Infant Memory

K. S. Grant, B. Crouthamel, C. Kenney, N. McKain, R. Petroff, S. Shum, J. Jing, N. Isoherranen, T. M. Burbacher

This study examines the effects of prenatal domoic acid exposure on neonatal behavior and memory in monkeys, finding impaired recognition memory at higher doses.

Neurotoxicology and Teratology · May 1, 2019Peer-reviewedPharmacology & Toxicology

Chronic, Low-Level Oral Exposure to Marine Toxin, Domoic Acid, Alters Whole Brain Morphometry in Nonhuman Primates

R. Petroff, T. Richards, B. Crouthamel, N. McKain, C. Stanley, K. S. Grant, S. Shum, J. Jing, N. Isoherranen, T. M. Burbacher

This study examines the effects of chronic low-level domoic acid exposure on brain structure and chemistry in nonhuman primates, finding correlations between tremors and reduced fractional anisotropy and increased lactate levels.

bioRxiv · Jan 25, 2019Pharmacology & Toxicology

Effects of Oral Domoic Acid Exposure on Maternal Reproduction and Infant Birth Characteristics in a Preclinical Nonhuman Primate Model

T. M. Burbacher, K. S. Grant, R. Petroff, S. Shum, B. Crouthamel, C. Stanley, N. McKain, J. Jing, N. Isoherranen

This study examines the effects of chronic low-dose domoic acid exposure on maternal reproduction and infant birth characteristics in nonhuman primates, finding no reproductive or physical developmental effects but subtle neurological effects in adult females.

bioRxiv · Oct 11, 2018Pharmacology & Toxicology