Development and applications of chimera platforms for tyrosine phosphorylation
R. Pergu, V. M. Shoba, S. K. Chaudhary, D. N. P. M. Godage, A. Deb, S. Singha, U. Dhawa, V. Anokhina, S. Singh, S. U. Siriwardena, A. Choudhary
This paper develops two platforms to create chimeric small molecules that induce tyrosine phosphorylation, demonstrating their ability to trigger phosphorylation and biological activities in target proteins.
bioRxiv · Mar 5, 2023Biochemistry