Author

A. J. Finch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. M. Magee· 1 shared A. Rio-Machin· 1 shared A. Tailleux· 1 shared A. von Kriegsheim· 1 shared B. Emerson· 1 shared B. Pate· 1 shared B. Peck· 1 shared B. Staels· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCancer Biology

A. M. Magee

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Author profile →

3 papers

Recent·Most cited

SCD inhibition eradicates AML displaying high de novo fatty acid desaturation and synergizes with chemotherapy

V. Dembitz, H. Lawson, R. Burt, C. Philippe, S. C. James, S. Atkinson, J. Durko, L. M. Wang, J. Campos, A. M. Magee, K. Woodley, M. J. Austin, A. Rio-Machin, P. Casado-Izquierdo, F. Bewicke-Copley, , P. Gallipoli

SCD inhibition induces AML cell death and synergizes with chemotherapy to prolong survival in murine AML models.

bioRxiv · Aug 2, 2023Cancer Biology

The hepatic compensatory response to elevated systemic sulfide promotes diabetes

R. N. Carter, M. T. G. Gibbins, M. E. Barrios-Llerena, S. E. Wilkie, P. L. Freddolino, M. Libiad, V. Vitvitsky, B. Emerson, T. Le Bihan, M. Brice, H. Su, S. G. Denham, N. Z. M. Homer, C. Mc Fadden, A. Tailleux, , N. M. Morton

This study shows that mice lacking the sulfide oxidation pathway enzyme TST exhibit metabolic abnormalities despite insulin sensitization, highlighting TST's role in hepatic metabolism and potential implications for sulfide-donor therapies.

bioRxiv · Apr 27, 2020Physiology

The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype.

P. Hari, F. R. Millar, N. Tarrats, J. Birch, C. J. Rink, I. Fernandez-Duran, M. Muir, A. J. Finch, V. G. Brunton, J. F. Passos, J. P. Morton, L. Boulter, J. C. Acosta

This study identifies TLR2 as a key mediator of oncogene-induced senescence by promoting cell cycle arrest and regulating the senescence-associated secretory phenotype through DAMPs.

Science Advances · Jun 1, 2019Peer-reviewedCell Biology