S. Srinivasan

The paper introduces iSAVE, a system to safely use a single ventilator for multiple patients during ventilator shortages, demonstrating its effectiveness in simulated and pig trials.

This study investigates zoonotic tuberculosis in India by analyzing human and cattle Mycobacterium tuberculosis complex isolates, finding no M. bovis in humans and highlighting the presence of M. orygis and M. tuberculosis in both species.

KnowEnG is a cloud-based platform that provides tools for analyzing genomics data using knowledge-guided data-mining and machine learning, demonstrating its utility in cancer research.

This study shows that Mtb exosomes reactivate HIV-1 by altering redox potential and bioenergetics, with antioxidant and host factor inhibitors reducing reactivation.

The paper uses a transgenic mouse model to show RBC-derived extracellular vesicles target cardiomyocytes and microglia in ischemic heart failure, with targeted cells showing gene enrichment in proliferation and metabolism.

The paper identifies a feedback mechanism linking intestinal peroxisomal fatty acid β-oxidation to neural serotonin signaling in C. elegans, affecting feeding and egg-laying behaviors.

The paper combines 16S rRNA gene amplicon sequencing with total bacterial load estimates to infer absolute species concentrations in the vaginal microbiome, showing good correlation with targeted qPCR for relative abundances above 10%.

This study develops a two-phase thin-film model to explain bacterial swarm and biofilm dynamics by integrating hydrodynamics, osmotic flux, and nutrient transport.

This study identifies a non-scission role for dynamin-1 in regulating early stages of clathrin-mediated endocytosis in non-neuronal cells through interactions with SNX9.

This study shows that EPS matrix production in Bacillus subtilis biofilms occurs at a propagating front, with gene expression waves coordinating sporulation and matrix production.