S. V. Kuchipudi

This study designs SARS-CoV-2 vaccines targeting conserved spike protein regions to reduce mutation escape, using epitope grafting on diverse scaffolds and showing immune response and diagnostic utility.

The paper introduces a CNN model to predict RBD-hACE2 binding affinity changes for SARS-CoV-2 variants, achieving high accuracy and identifying variants with improved binding affinity.

The paper shows SARS-CoV-2 Omicron variant infects white-tailed deer on Staten Island, with age-dependent antibody prevalence and evidence of human-to-deer spillover.

SARS-CoV-2 was detected in one-third of sampled white-tailed deer in Iowa between September 2020 and January of 2021 that likely resulted from multiple human-to-deer spillover and deer-to-deer transmission events.

The paper predicts the effect of amino acid changes on SARS-CoV-2 spike protein binding to hACE2 using molecular dynamics and a neural network, achieving 82.2% classification accuracy and 0.69 correlation with experimental data.

This study investigates the association between influenza C and D viral loads and bovine respiratory disease in cattle, finding higher viral loads and coinfections in BRD-symptomatic animals.

The study evaluates anti-SARS-CoV-2 antibody and neutralizing titer profiles in convalescent plasma samples to determine the optimal donation window for immunotherapy.

This study finds a strong correlation between anti-RBD and anti-ECD IgG titers and in vitro virus neutralization titers in convalescent plasma, suggesting these titers can serve as surrogates for neutralizing activity.