ER-to-lysosome Ca2+ refilling followed by K+ efflux-coupled store-operated Ca2+ entry in inflammasome activation and metabolic inflammation
H. Kang, S. W. Choi, J. Y. Kim, S.-J. Oh, S. J. Kim, M.-s. Lee
This study identifies a novel mechanism involving lysosomal Ca2+ release and K+ efflux through KCa3.1 channels in inflammasome activation and metabolic inflammation.
eLife · Jul 2, 2024Peer-reviewedImmunology