Exchange protein directly activated by cAMP plays a critical role in regulation of vascular fibrinolysis
X. He, A. Drelich, Q. Chang, D. Gong, Y. Zhou, Y. Qu, S. Yu, Y. Yang, J. Qian, Y. Qiu, S.-J. Tang, A. Gaitas, T. Ksiazek, Z. Xu, M. Wakamiya, , B. Gong
This study shows that EPAC1 promotes ANXA2 translocation to endothelial cell surfaces, enhancing plasminogen to plasmin conversion and fibrinolysis.
bioRxiv · Oct 1, 2017Cell Biology